Results 31 to 40 of about 1,170,009 (287)
Summary: We combined CAGE sequencing in human adipocytes during differentiation with data from genome-wide association studies to identify an enhancer in the SNX10 locus on chromosome 7, presumably involved in body fat distribution. Using reporter assays
Casimiro Castillejo-Lopez+8 more
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Null alleles are alleles that are recessive to codominant markers without any effect on the phenotype. In SSR assays, there are several reasons for the lack of amplification at a locus: the primer does not bind well, longer fragments do not amplify due ...
Gizella Jahnke+5 more
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Including copy number variation in association studies to predict genotypic values [PDF]
The objective of this study was to investigate, both empirically and deterministically, the ability to explain genetic variation resulting from a copy number polymorphism (CNP) by including the CNP, either by its genotype or by a continuous derivation ...
Calus, M.P.L.+2 more
core +2 more sources
Genetic diversity at the HUMTHO1 locus
A World-wide population genetic study on the highly polymorphic DNA locus HUMTHO1, was performed using data collected from 48 studies. Also this study reports new allele frequency data of a Punjabi population (n = 125) from North India. This population is in Hardy-Weinberg equilibrium with 77.6% heterozygosity and power of exclusion at 0.538.
P. Gill+2 more
openaire +3 more sources
Reinforcement of genetic coherence in a two-locus model [PDF]
In order to maintain populations as units of reproduction and thus enable anagenetic evolution, genetic factors must exist which prevent continuing reproductive separation or enhance reproductive contact. This evolutionary principle is called genetic coherence and it marks the often ignored counterpart of cladistic evolution.
Gregorius, Hans-Rolf, Steiner, Wilfried
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Adaptive topographies and equilibrium selection in an evolutionary game. [PDF]
It has long been known in the field of population genetics that adaptive topographies, in which population equilibria maximise mean population fitness for a trait regardless of its genetic bases, do not exist.
Hinke M Osinga, James A R Marshall
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Genetic Analysis of Mitochondrial Sorting from the MSC3 Mosaic Mutant of Cucumber
Cucumber (Cucumis sativus) plants regenerated from cell cultures occasionally possess mosaic (MSC) phenotypes on cotyledons and leaves. Lines MSC3 and MSC16 have distinct MSC phenotypes and originated from plants regenerated from different cell-culture ...
Lyle T. Wallace, Michael J. Havey
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Genetic variation in the porcine myogenin gene locus [PDF]
ISSN:1432 ...
Soumillion, A.+4 more
openaire +7 more sources
lociNGS: a lightweight alternative for assessing suitability of next-generation loci for evolutionary analysis. [PDF]
Genomic enrichment methods and next-generation sequencing produce uneven coverage for the portions of the genome (the loci) they target; this information is essential for ascertaining the suitability of each locus for further analysis.
Sarah M Hird
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Mutation analysis of 21 autosomal short tandem repeats in Han population from Hunan, China
Background: Short tandem repeats (STRs) are powerful genetic markers widely used in human genetics. Population data and locus-specific mutation rates of STRs are crucial for the evaluation and interpretation of genetic evidence in forensic and population
Wei Xu+7 more
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