Results 41 to 50 of about 1,170,009 (287)

Using bioinformatics and systems genetics to dissect HDL-cholesterol genetics in an MRL/MpJ × SM/J intercross[S]

open access: yesJournal of Lipid Research, 2012
A higher incidence of coronary artery disease is associated with a lower level of HDL-cholesterol. We searched for genetic loci influencing HDL-cholesterol in F2 mice from a cross between MRL/MpJ and SM/J mice.
Magalie S. Leduc   +6 more
doaj   +1 more source

Recent and Ancient Signature of Balancing Selection around the S-Locus in Arabidopsis halleri and A. lyrata [PDF]

open access: yes, 2012
Balancing selection can maintain different alleles over long evolutionary times. Beyond this direct effect on the molecular targets of selection, balancing selection is also expected to increase neutral polymorphism in linked genome regions, in inverse ...
Castric, Vincent   +5 more
core   +3 more sources

GENETIC CHANGE IN MUTATIONS AT THE T/t-LOCUS IN THE MOUSE [PDF]

open access: yesGenetics, 1976
ABSTRACT Recessive lethal or semilethal alleles at the T/t locus in the mouse generate new t-variants, with characteristics different from the parent allele at a rate of about 10-3. Almost invariably the variant chromosome carries marker genes derived from the opposite parental chromosome.
Bennett, D, Dunn, L C, Artzt, K
openaire   +2 more sources

Using Gene Editing to Establish a Safeguard System for Pluripotent Stem-Cell-Based Therapies

open access: yesiScience, 2019
Summary: A major challenge in using human pluripotent stem cells (hPSCs) in therapy is the risk of teratoma formation due to contaminating undifferentiated stem cells. We used CRISPR-Cas9 for in-frame insertion of a suicide gene, iC9, into the endogenous
Youjun Wu   +5 more
doaj   +1 more source

Irradiation induced inversions suppress recombination between the M locus and morphological markers in Aedes aegypti

open access: yesBMC Genetics, 2020
Background Aedes aegypti is the primary vector of arthropod-borne viruses and one of the most widespread and invasive mosquito species. Due to the lack of efficient specific drugs or vaccination strategies, vector population control methods, such as the ...
Antonios A. Augustinos   +5 more
doaj   +1 more source

Analisis Keanekaragaman Genetik dan Diferensiasi Jati Jawa dan Madura berdasarkan Marka Mikrosatelit untuk Mendukung Fingerprinting Jati

open access: yesBiosaintifika: Journal of Biology & Biology Education, 2010
Analysis fingerprinting teak is supported by information about teak’s character molecularly. The information is gotten by analyzing 3 primary microsatellite in 46 teak samples that produce total 18 kinds of alel averagely 6 alel per locus.
Munisyatul Millah   +2 more
doaj   +1 more source

QTL discovery for resistance to black spot and cercospora leaf spot, and defoliation in two interconnected F1 bi-parental tetraploid garden rose populations

open access: yesFrontiers in Plant Science, 2023
Garden roses are an economically important horticultural crop worldwide, and two major fungal pathogens, black spot (Diplocarpon rosae F.A. Wolf) and cercospora leaf spot of rose (Rosisphaerella rosicola Pass.), affect both the health and ornamental ...
Jeekin Lau   +6 more
doaj   +1 more source

Breeding, genetics, and genomics for tolerance against terminal heat in lentil: Current status and future directions

open access: yesLegume Science, 2020
Heat stress at terminal stage in lentil is one of the major factors causing drastic yield loss. Development of heat tolerant cultivars is one of the ways to tackle this problem.
Jitendra Kumar   +2 more
doaj   +1 more source

Long‐read genotyping with SLANG (Simple Long‐read loci Assembly of Nanopore data for Genotyping)

open access: yesApplications in Plant Sciences, 2022
Premise Most phylogenomic library preparation methods and bioinformatic analysis tools in restriction site–associated DNA sequencing (RADseq)/genotyping‐by‐sequencing (GBS) studies are designed for use with Illumina data.
Marco Dorfner   +3 more
doaj   +1 more source

Genetic regulation of the intercellular adhesion locus in staphylococci [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
The formation of biofilms by Staphylococcus aureus and Staphylococcus epidermidis is an important aspect of many staphylococcal infections, most notably endocarditis, osteomyelitis and infections associated with indwelling medical devices. The major constituents of staphylococcal biofilms are polysaccharides, such as poly N-acetyl glucosamine (PIA/PNAG)
David Cue, Chia Y. Lee, Mei G. Lei
openaire   +4 more sources

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