Results 71 to 80 of about 1,170,009 (287)

Rapid adaptation of a polygenic trait after a sudden environmental shift

, 2017
Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core   +1 more source

forqs: Forward-in-time Simulation of Recombination, Quantitative Traits, and Selection [PDF]

, 2013
forqs is a forward-in-time simulation of recombination, quantitative traits, and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations ...
Kessner, Darren, Novembre, John
core  

Dispersal and population structure at different spatial scales in the subterranean rodent Ctenomys australis [PDF]

, 2010
This study was funded by grants from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET, PIP5838), Agencia de Promoción Científica y Tecnológica de la Argentina (PICTO1-423, BID-1728/OC-AR), and the programme ECOS-Sud France/Argentina ...
Gaggiotti, Oscar E., Kittlein, Marcelo J., Lessa, Enrique P., Mapelli, Fernando J., Mora, Matias S.   +4 more
core   +1 more source

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

PLoS Genetics, 2013
Polycomb group (PcG) proteins are essential for the repression of key factors during early development. In Drosophila, the polycomb repressive complexes (PRC) associate with defined polycomb response DNA elements (PREs). In mammals, however, the mechanisms underlying polycomb recruitment at targeted loci are poorly understood.
Patrick Schorderet, Sandra Gitto, Fabrice Darbellay, Natalia Soshnikova, Denis Duboule, Denis Duboule, Patrick Tschopp, Nicolas Lonfat   +7 more
openaire   +6 more sources

Fast and cost-effective mining of microsatellite markers using NGS technology: an example of a Korean water deer Hydropotes inermis argyropus. [PDF]

PLoS ONE, 2011
BACKGROUND: Microsatellites, a special class of repetitive DNA sequence, have become one of the most popular genetic markers for population/conservation genetic studies.
Jeong-Nam Yu, Changman Won, Jumin Jun, Youngwoon Lim, Myounghai Kwak   +4 more
doaj   +1 more source

Statistics of selectively neutral genetic variation

, 2001
Random models of evolution are instrumental in extracting rates of microscopic evolutionary mechanisms from empirical observations on genetic variation in genome sequences.
A. H. D. Brown, B. Haubold, C. Wiuf, E. S. Lander, G. A. Watterson, G. P. Patil, J. C. Venter, J. F. C. Kingman, J. Maynard Smith, K. E. Dingle, M. Bahlo, M. C. J. Maiden, M. Kimura, M. Kreitman, N. Takahata, P. A. Fuerst, P. Donnelly, R. Arratia, R. R. Hudson, T. Ohta, Th. Wiehe, V. Souza   +21 more
core   +1 more source

A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease [PDF]

, 2015
Existing knowledge of genetic variants affecting risk of coronary artery disease (CAD) is largely based on genome-wide association studies (GWAS) analysis of common SNPs.
Alver, M, Anand, SS, Ardissino, D, Armasu, SM, Assimes, TL, Auro, K, Bertram, L, Beutner, F, Bjonnes, A, Boerwinkle, E, Borecki, IB, Bottinger, EP, Buring, JE, Chambers, JC, Chasman, DI, Chen, S, Clarke, R, Collins, R, Consortium, C, Cupples, LA, Danesh, J, de Andrade, M, de Vries, PS, Dedoussis, G, Dehghan, A, Deloukas, P, Demuth, I, Elosua, R, Epstein, SE, Erdmann, J, Esko, T, Farrall, M, Feitosa, MF, Ford, I, Franceschini, N, Franco, OH, Franzosi, MG, Frossard, P, Gauguier, D, Gieger, C, Goel, A, Goodall, AH, Gottesman, O, Grace, C, Granger, CB, Gu, D, Gudnason, V, Gustafsson, S, Haber, M, Hall, AS, Hall, LM, Hamsten, A, Han, B-G, Harris, TB, Hazen, SL, Hengstenberg, C, Hofman, A, Hopewell, JC, Huang, J, Huang, J, Hwang, S-J, Ingelsson, E, Iribarren, C, Jalilzadeh, S, Jukema, JW, Kanoni, S, Karhunen, PJ, Kathiresan, S, Kessler, T, Kim, B-J, Kim, YK, Kleber, ME, Koenig, IR, Kooner, JS, Kullo, IJ, Kyriakou, T, Lannfelt, L, Lau, KW, Lehtimaki, T, Lieb, W, Lind, L, Lindgren, CM, Lokki, M-L, Loos, RJF, Lu, X, Lu, Y, Lyytikainen, L-P, Maerz, W, Magnusson, PK, Mallick, NH, McPherson, R, Mehra, N, Meitinger, T, Melander, O, Memon, F-U-R, Metspalu, A, Mihailov, E, Morris, AP, Morrison, AC, Nelson, CP, Nieminen, MS, Nikpay, M, O'Donnell, CJ, Palmer, CN, Pedersen, NL, Perola, M, Pervjakova, N, Peters, A, Qu, L, Quertermous, T, Rader, DJ, Rallidis, LS, Rasheed, A, Reilly, MP, Ridker, PM, Ripatti, S, Roberts, R, Rose, LM, Saleheen, D, Salfati, E, Salomaa, V, Samani, NJ, Samuel, M, Sanghera, DK, Saxena, R, Scholz, M, Schunkert, H, Schwartz, SM, Seedorf, U, Shah, SH, Sinisalo, J, Smith, AV, Stewart, AF, Stirrups, KE, Stott, DJ, Thiery, J, Thompson, JR, Tikkanen, E, Trompet, S, Uitterlinden, A, van Zuydam, NR, Wang, L, Watkins, H, Webb, TR, Willenborg, C, Won, H-H, Yang, X, Zalloua, PA, Zaman, KS, Zeng, L, Zhang, W, Zhao, W   +151 more
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Locus of Control and Obesity

Frontiers in Endocrinology, 2014
In the developed world, the hazards associated with obesity have largely outstripped the risk of starvation. Obesity remains a difficult public health issue to address, due in large part to the many disciplines involved.
Florence eNeymotin, Louis R Nemzer
doaj   +1 more source

The Tabby cat locus maps to feline chromosome B1. [PDF]

, 2006
The Tabby markings of the domestic cat are unique coat patterns for which no causative candidate gene has been inferred from other mammals. In this study, a genome scan was performed on a large pedigree of cats that segregated for Tabby coat markings ...
Bach, L, Bailey, S, Baysac, K, Byrns, G, Erdman, C, Fretwell, N, Froenicke, L, Gazlay, K, Geary, L, Grahn, J, Grahn, R, Karere, G, Lipinski, M, Lyons, Leslie, Rah, H, Ruhe, M   +15 more
core  

QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains [PDF]

, 2009
Peer reviewedPublisher ...
Blizard, David A, Koide, Tsuyoshi, Kuriki, Satoshi, Lionikas, Arimantas, Nishi, Akinori, Sakaguchi, Takayuki, Umemori, Juzoh   +6 more
core   +3 more sources