Results 81 to 90 of about 1,170,009 (287)

The Genetic Determinism of Biochemical Systems Polymorphous From the Blood Serum in Pigs

Scientific Papers Animal Science and Biotechnologies, 2023
The study of genetic markers and identification of new markers make the subject of an increasing number of research projects in various fields such as genetics of immunology, biochemical genetics, molecular genetics, quantitative genetics and the genetic
Nicoleta Işfan, Dana Popa, Razvan Popa, Carmen Nicolae, Monica Marin, Marius Maftei   +5 more
doaj  

Molecular genetics is on the guard of the law

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Molecular genetics is one of the key tools of modern medicine. With its help, scientists can study the structure and function of DNA, decode genetic codes, and develop new treatments.
L. I. Kucherenko, I. V. Pavliuk, O. V. Khromylova   +2 more
doaj   +1 more source

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. [PDF]

, 2019
Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects.
Alver, Maris, Amin, Najaf, Amini, Marzyeh, Arnett, Donna K, Aschard, Hugues, Aslibekyan, Stella, Bartz, Traci M, Bentley, Amy R, Bielak, Lawrence F, Boerwinkle, Eric, Boissel, Mathilde, Brown, Michael R, Brumat, Marco, Cade, Brian, Campbell, Archie, Canouil, Mickaël, Chai, Jin Fang, Chasman, Daniel I, Chen, Xu, Chen, Yii-Der Ida, Concas, Maria Pina, Connell, John, de Las Fuentes, Lisa, de Mutsert, Renée, de Silva, H Janaka, de Vries, Paul S, Demirkan, Ayşe, Ding, Jingzhong, Divers, Jasmin, Dorajoo, Rajkumar, Eaton, Charles B, Evangelou, Evangelos, Faul, Jessica D, Feitosa, Mary F, Fisher, Virginia, Franceschini, Nora, Friedlander, Yechiel, Gabriel, Kelley P, Gao, Chuan, Ghanbari, Mohsen, Giulianini, Franco, Graff, Mariaelisa, Gu, Chi Charles, Gu, Dongfeng, Guo, Xiuqing, Harris, Sarah E, Harris, Tamara B, Hartwig, Fernando P, He, Jiang, He, Meian, Heikkinen, Sami, Heng, Chew-Kiat, Horimoto, Andrea RVR, Hsu, Fang-Chi, Hunt, Steven C, Ikram, M Arfan, Jackson, Anne U, Jakupović, Hermina, Jonas, Jost B, Kho, Minjung, Kilpeläinen, Tuomas O, Koh, Woon-Puay, Komulainen, Pirjo, Kraja, Aldi T, Krieger, Jose E, Kühnel, Brigitte, Laguzzi, Federica, Li, Changwei, Li, Xiaoyin, Lohman, Kurt K, Lyytikäinen, Leo-Pekka, Manning, Alisa, Marten, Jonathan, Musani, Solomon K, Nolte, Ilja M, Noordam, Raymond, Ntalla, Ioanna, Rauramaa, Rainer, Riaz, Muhammad, Richard, Melissa, Robino, Antonietta, Rueedi, Rico, Schwander, Karen, Sim, Xueling, Smith, Albert V, Stringham, Heather M, Sung, Yun Ju, Tajuddin, Salman M, Takeuchi, Fumihiko, van der Most, Peter J, Varga, Tibor V, Verweij, Niek, Vojinovic, Dina, Wang, Heming, Wang, Zhe, Ware, Erin B, Wen, Wanqing, Winkler, Thomas W, Yanek, Lisa R, Zhao, Jing Hua   +99 more
core  

Genetic determinants of cortical structure (thickness, surface area and volumes) among disease free adults in the CHARGE Consortium [PDF]

, 2019
Cortical thickness, surface area and volumes (MRI cortical measures) vary with age and cognitive function, and in neurological and psychiatric diseases.
Adams, H., Ahmad, S., Ames, D., Amin, N., Amouye, P., Andreassen, O., Armstrong, N., Bastin, M., Becker, J., Beiser, A., Bernard, M., Beyer, F., Bis, J., Bralten, J., Brodaty, H., Bülow, R., Carmichael, O., Colodro-Conde, L., Crivello, F., Dale, A., Deary, I., Debette, S., DeCarli, C., Fornage, M., Franz, C., Gillespie, N., Grabe, H., Grasby, K., Harris, M., Hibar, D., Himali, J., Hofer, E., Hofman, A., Ikram, M., Jahanshad, N., Jian, X., Jiang, J., Karama, S., Knol, M., Kremen, W., Kwok, J., Lewis, L., Li, S., Lin, H., Lind, P., Loeffler, M., Logue, M., Longstreth Jr., W., Lopez, O., Luciano, M., Lyons, M., Maillard, P., Maingault, S., Mather, K., Mazoyer, B., Medland, S., Mishra, A., Mosley, T., Neale, M., Niessen, W., Painter, J., Panizzon, M., Paus, T., Pausova, Z., Pike, G., Pirpamer, L., Pizzagalli, F., Psaty, B., Roshchupkin, G., Rotter, J., Saba, Y., Sachdev, P., Satizabal, C., Schmid, R., Schmidt, H., Schofield, P., Scholz, M., Seiler, S., Seshadr, S., Stein, J., Teumer, A., Thalamuthu, A., Thompson, P., Trollor, J., Tzourio, C., Uitterlinden, A., van der Lee, S., van Duijn, C., Vernooij, M., Villringer, A., Völker, U., Wardlaw, J., Wen, W., Witte, A., Wittfeld, K., Wright, M., Xia, R., Yang, Q., Zare, H.   +98 more
core   +2 more sources

Robust forward simulations of recurrent hitchhiking [PDF]

, 2014
Evolutionary forces shape patterns of genetic diversity within populations and contribute to phenotypic variation. In particular, recurrent positive selection has attracted significant interest in both theoretical and empirical studies.
Hernandez, Ryan D., Uricchio, Lawrence H.   +1 more
core   +2 more sources

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Badenhoop, Klaus, Hahner, Stefanie, Kahles, Heinrich, Lange, Britta Kristina, Meyer, Gesine, Penna Martinez, Marissa, Ramos-Lopez, Elizabeth, Reisch, Nicole, Seissler, Jürgen, Willenberg, Holger S.   +9 more
core   +2 more sources

An efficient multi-locus mixed model approach for genome-wide association studies in structured populations

Nature Genetics, 2012
Population structure causes genome-wide linkage disequilibrium between unlinked loci, leading to statistical confounding in genome-wide association studies.
V. Segura, B. Vilhjálmsson, Alexander Platt, A. Korte, Ümit Seren, Q. Long, M. Nordborg   +6 more
semanticscholar   +1 more source

Por que o desenvolvimento ontogenético foi tratado como uma “caixa preta” na síntese moderna da evolução?

Principia: An International Journal of Epistemology, 2015
The Modern Evolutionary Synthesis relegated the ontogenetic development to a “black box”. In this article, we argue that the absence of ontogenetic development in the Evolutionary Synthesis was due its strong foundation in transmission genetics.
Leonardo Augusto Luvison Araújo, Aldo Mellender de Araújo   +1 more
doaj  

Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases

Cardiovascular Drugs and Therapy, 2016
Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein that is under strong genetic control by the LPA gene locus. Genetic variants including a highly polymorphic copy number variation of the so called kringle IV repeats at this locus have a ...
F. Kronenberg
semanticscholar   +1 more source

Complex Genetic Interactions in a Quantitative Trait Locus

PLoS Genetics, 2006
Whether in natural populations or between two unrelated members of a species, most phenotypic variation is quantitative. To analyze such quantitative traits, one must first map the underlying quantitative trait loci. Next, and far more difficult, one must identify the quantitative trait genes (QTGs), characterize QTG interactions, and identify the ...
Bradly P. Nicholson, John H. McCusker, Lars M. Steinmetz, Himanshu Sinha   +3 more
openaire   +5 more sources