Results 41 to 50 of about 226,214 (291)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Genetic structure and molecular mechanism underlying the stalk lodging traits in maize (Zea mays L.)
Computational and Structural Biotechnology Journal, 2023 Stalk lodging seriously affects yield and quality of crops, and it can be caused by several factors, such as environments, developmental stages, and internal chemical components of plant stalks.
Shuai Wang +6 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Agronomy, 2022 Much attention has shifted to the effects of temperature and solar radiation on rice production and grain quality due to global climate change. Meanwhile, lodging is a major cause of rice yield and quality losses.
Xiaoyun Luo +9 more
doaj +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Nature, 1885 PERMIT me to thank Prof. Tait for his kind and amusing criticism of my little book. I am struck with comic horror at the thought that anything in the preface can be construed into a comparison between works like Thomson and Tait, Clerk-Maxwell and W. K. Clifford, with such elementary picture-books as Deschanel and Ganot.
openaire +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Unraveling the central role of root morphology and anatomy in lodging of tef (Eragrostis tef)
Plants, People, PlanetSocietal Impact Statement Crop diversification is considered key to ensuring agricultural sustainability and food security. Tef (Eragrostis tef (Zucc.) Trotter) is a cereal crop grown mainly in Ethiopia, where it thrives in a wide range of environments ...
Shiran Ben‐Zeev +5 more
doaj +1 more source
AgronomyThis study explored the patterns and mechanisms influencing changes in silage quality, mycotoxin accumulation, and microbial community structure in oat silage after lodging.
Yongmei Jiang +8 more
doaj +1 more source
Boston Hospitality Review: Spring 2013 [PDF]
, 2013 Lodging Update: Providence, Rhode Island by Rachel Roginsky and Matthew Arrants -- Brand Heritage and Heritage Tourism by Bradford Hudson -- Te Front Desks of Boston by Michael Oshins -- Defining the New Luxury: Perspectives from Industry Leaders by ...
Arrants, Matthew +6 more
core +1 more source