Results 71 to 80 of about 226,214 (291)
PlantsLodging resistance is one of the most important traits of machine-picked cotton. Lodging directly affects the cotton yield, quality and mechanical harvesting effect. However, there are only a few reports on the lodging resistance of cotton. In this study,
Yuan Wang +6 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Morphological and physiological mechanisms underlying lodging in cotton stems
Journal of Cotton ResearchBackground Cotton lodging has become increasingly prevalent due to extreme environmental conditions and agronomic practices, severely compromising yield, fiber quality, and mechanical harvesting efficiency.
Xinghua Yu +9 more
doaj +1 more source
Organic Heirloom Spring Wheat Seeding Rate Trial [PDF]
, 2015 University of Vermont Extension began its heirloom spring wheat project in 2007 to determine whether heirloom varieties developed before 1950 could thrive in Vermont’s climate.
Calderwood, Lily +5 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Remote Sensing, 2018 Maize (zee mays L.) is one of the most important grain crops in China. Lodging is a natural disaster that can cause significant yield losses and threaten food security.
Liang Han +7 more
doaj +1 more source
Penerapan Cloud Computing Pada Sistem Reservasi Homestay Dieng Berbasis Web [PDF]
, 2017 Homestay is one of the places needed as lodging facilities in the tourist area. In recent years, lodging business is greatly increasing. Business lodging in Dieng is one of the promising venture business' due to the increasing number of the tourists who ...
Umar, Alan Fajar Sudrajat, Rusydi
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
RUDN Journal of Agronomy and Animal Industries, 2018 The main direction of breeding grain crops is to increase yield and improve grain quality. For maximum crop yield, it is necessary to develop cultivars with high productivity and quality potential, resistant to biotic and abiotic environmental factors ...
Elmira Rubenovna Avakyan +1 more
doaj +1 more source