Results 111 to 120 of about 66,966 (283)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Characteristics of Lodging Resistance of Wheat Cultivars from Different Breeding Decades as Affected by the Application of Paclobutrazol Under Shading Stress

Agronomy
Low solar radiation, caused by climate change or dense planting patterns, now limits wheat production. Although wheat breeding has increased lodging resistance and yield potential through the introduction of dwarfing genes, it still reduces wheat yields.
Dianliang Peng, Haicheng Xu, Zhen Guo, Wenchao Cao, Jingmin Zhang, Mei Liu, Xingcui Wang, Yuhai Tang, Tie Cai   +8 more
doaj   +1 more source

Transfer of a major dominant gene for resistance to eyespot disease from a wild grass to hexaploid wheat [PDF]

, 1983
Eyespot disease, caused by the fungus Pseudocercosporella herpotrichoides, is responsible for considerable lodging and reductions of yield in extensive areas of wheat cultivation in North and South America, Europe, New Zealand, Australia and Africa1. The
A Delibes, A Delibes, A Delibes, A Delibes, A. Delibes, CN Law, F Dosba, F Dosba, F Dosba, F. Garcia-Olmedo, G Kimber, G. Doussinault, J Jahier, MV Wiese, N Maia, R Sprague, R. Sanchez-Monge   +16 more
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

What should organic farmers grow: heritage or modern spring wheat varieties? Report from a study comparing yields, grain and bread quality [PDF]

, 2019
For a 100% organic value chain, we need more varieties suitable for organic cultivation. Varieties bred for organic growing is a challenge in small markets. Many breeding goals are equal for organic and conventional cereals.
Dieseth, Jon Arne, Frøseth, Randi Berland, Lindö, Caroline, Løes, Anne-Kristin, Skaret, Josefine   +4 more
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Impact of High Glucosinolate Mustard Biomass and Meal on Black Bean Yield [PDF]

, 2013
Brassicae crops (mustard family) contain chemicals called glucosinolates. These compounds are present in the leaves, stem, roots, and seed of the plants.
Cummings, Erica, Darby, Heather, Harwood, Hannah, Monahan, Susan   +3 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Optimized nitrogen and potassium fertilizers application increases stem lodging resistance and grain yield of oil flax by enhancing lignin biosynthesis

Journal of Integrative Agriculture
Lodging is a major constraint limiting oil flax production efficiency in northern China. Crop lodging susceptibility is closely related to stem lignin content, and the regulatory mechanisms by which nitrogen and potassium fertilization interactively ...
Xiqiang Li, Yuhong Gao, Zhengjun Cui, Tingfeng Zhang, Shiyuan Chen, Shilei Xiang, Lingling Jia, Bin Yan, Yifan Wang, Lizhuo Guo, Bing Wu   +10 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source