Results 41 to 50 of about 34,114 (259)

Aplikasi Pupuk Organik Cair Menggunakan Bioaktivator Mikroorganisme Indigenous HPPB Untuk Pertumbuhan Desmodium heterophyllum pada Tanah Bekas Tambang Batu Kapur PT. Semen Padang

Jurnal Biologi Universitas Andalas, 2018
The research about application of liquid organic fertilizers with indigenous microorganism bioactivator of HPPB for growth of Desmodium heterophyllum on limestone mined land at PT.
Rizqa Zidna Chairafahmi, Suwirmen Suwirmen, Zozy Aneloi Noli   +2 more
doaj   +1 more source

Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Genome Medicine, 2023
Gain-of-function (GOF) variants give rise to increased/novel protein functions whereas loss-of-function (LOF) variants lead to diminished protein function.
David Stein, Meltem Ece Kars, Yiming Wu, Çiğdem Sevim Bayrak, Peter D. Stenson, David N. Cooper, Avner Schlessinger, Yuval Itan   +7 more
doaj   +1 more source

Corporate social responsibility, organisational reputation and liability of foreignness

South African Journal of Business Management, 2021
Purpose: This study aimed to test the impact of corporate social responsibility (CSR) and its subdivision dimensions on the liability of foreignness (LOF), as well as the mediating effect of organisational reputation.
Yuting Zhang, Yunlong Jiang
doaj   +1 more source

Computational protein stability analysis of SCN1A missense variants reveals domain-dependent stability patterns. [PDF]

Epilepsia Open
Abstract Objective To determine whether computational protein‐stability predictions discriminate pathogenic from benign SCN1A missense variants, and to characterize the structural distribution of predicted destabilization among pathogenic variants. Methods On an AlphaFold3‐predicted Nav1.1 structure, FoldX, and Rosetta Cartesian ΔΔG were computed for a
Shim Y, Kang E, Kwak N, Kim S.
europepmc   +2 more sources

LOFS: A library of online streaming feature selection [PDF]

Knowledge-Based Systems, 2016
As an emerging research direction, online streaming feature selection deals with sequentially added dimensions in a feature space while the number of data instances is fixed. Online streaming feature selection provides a new, complementary algorithmic methodology to enrich online feature selection, especially targets to high dimensionality in big data ...
Kui Yu, Wei Ding 0003, Xindong Wu 0001
openaire   +3 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Discontinuous Shear Thickening in Cornstarch Suspensions

EPJ Web of Conferences, 2017
We study the emergence of discontinuous shear-thickening (DST) in cornstarch, the well know system for this phenomenon, by combining macroscopic rheometry with local Magnetic Resonance Imaging (MRI) measurements. We bring evidence that macroscopic DST is
Fall Abdoulaye, Lemaître Anaël, Ovarlez Guillaume   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Lof Paichil Antreao: Comunidad mapuche ancestral de la región de Villa la Angostura [PDF]

, 2019
El libro reúne los conocimientos de los intergrantes del Lof Paichil Antreao y de diversos investigadores de la UBA en torno a la historia indígena regional y en particular sobre la trayectoria histórica de este Lof, la que permite sostener su derecho a ...
Ramos, Mariano, Stecher, Gabriel Andre, Olivero, Damian, Trinchero, Hector Hugo, Ghioldi, Gerardo, Balazote, Alejandro, de Jong, Ingrid Lilia, Tropan, Soledad, Radovich, Juan Carlos, Subiri, Laura, Maragliano, Graciela, Pérez, Alejandra, Loncón, Lorenzo, Márquez, Verónica, Valverde, Sebastián, Varisco, Sofía, Nahuel, Florentino, Impemba, Marcelo, Collinao, Francisco   +18 more
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source