Results 41 to 50 of about 356,775 (283)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A new Maxwell-Log logistic distribution and its applications for mortality rate data

Journal of Nigerian Society of Physical Sciences
In this research, we extended the Log-Logistic distribution by incorporating it into the Maxwell generalized class, resulting in the Maxwell-Log Logistic (Max-LL ) distribution.
Uthumporn Panitanarak, Aliyu Ismail Ishaq, Alfred Adewole Abiodun, Hanita Daud, Ahmad Abubakar Suleiman   +4 more
doaj   +1 more source

On the contraction properties of some high-dimensional quasi-posterior distributions [PDF]

, 2016
We study the contraction properties of a quasi-posterior distribution $\check\Pi_{n,d}$ obtained by combining a quasi-likelihood function and a sparsity inducing prior distribution on $\rset^d$, as both $n$ (the sample size), and $d$ (the dimension of ...
Atchadé, Yves F.
core  

Grid multi-category response logistic models. [PDF]

, 2015
BackgroundMulti-category response models are very important complements to binary logistic models in medical decision-making. Decomposing model construction by aggregating computation developed at different sites is necessary when data cannot be moved ...
Jiang, Wenchao, Jiang, Xiaoqian, Li, Pinghao, Ohno-Machado, Lucila, Wang, Shuang, Wu, Yuan   +5 more
core   +1 more source

The beta log-logistic distribution

Brazilian Journal of Probability and Statistics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Frailty Exacerbates Disability in Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks, Anna Wolska, Diala Ghazal, Dejan Jakimovski, Bianca Weinstock‐Guttman, Alexander Burnham, Niels Bergsland, Michael G. Dwyer, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +10 more
wiley   +1 more source

Optimization of Gamma–Power–Log–logistic distribution and its applications in modelling volume of oil spillage

Scientific African, 2023
Oil spillage is one of the major problems in the Niger Delta region of Nigeria, which have affected human health and aquaculture. There is a need to estimate the volume of spill per incidence.
M.I. Ekum, E.E.E. Akarawak, M.O. Adamu
doaj   +1 more source

Detecting epistasis via Markov bases [PDF]

, 2010
Rapid research progress in genotyping techniques have allowed large genome-wide association studies. Existing methods often focus on determining associations between single loci and a specific phenotype.
Malaspinas, Anna-Sapfo, Uhler, Caroline
core   +1 more source

The Odd Log-Logistic Log-Normal Distribution with Theory and Applications

Advances in Data Science and Adaptive Analysis, 2018
In this paper, a new heavy-tailed distribution is used to model data with a strong right tail, as often occuring in practical situations. The proposed distribution is derived from the log-normal distribution, by using odd log-logistic distribution. Statistical properties of this distribution, including hazard function, moments, quantile function, and ...
Ozel, Gamze, Altun, Emrah, Alizadeh, Morad, Mozafari, Mahdieh   +3 more
openaire   +3 more sources

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source