Results 41 to 50 of about 144,366 (260)
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Common statistical errors in logarithmic data of viral load
Background: The mathematical operation of logarithm data follows the rules of logarithm as the numbers relate to specific meanings. The numbers prior to the decimal are the mantissa or the transformed power of 10 and the numbers after the decimal are the
Suthon Vongsheree
doaj
Solution to an open problem on a logarithmic integral and derived results
This article solves an open problem that was previously stated by providing an exact evaluation of a logarithmic integral. Furthermore, the result is generalized by introducing a new adjustable parameter.
Coine Clément, Chesneau Christophe
doaj +1 more source
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Logarithm of the Discrete Fourier Transform
The discrete Fourier transform defines a unitary matrix operator. The logarithm of this operator is computed, along with the projection maps onto its eigenspaces. A geometric interpretation of the discrete Fourier transform is also given.
Michael Aristidou, Jason Hanson
doaj +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Exponential and logarithm of multivector in low-dimensional (n = p + q < 3) Clifford algebras
The aim of the paper is to give a uniform picture of complex, hyperbolic, and quaternion algebras from a perspective of the applied Clifford geometric algebra.
Adolfas Dargys, Artūras Acus
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
An explicit formula for the matrix logarithm
No Abstract ...
João R Cardoso
doaj +1 more source

