Results 41 to 50 of about 144,366 (260)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Common statistical errors in logarithmic data of viral load

open access: yesJournal of Associated Medical Sciences, 2018
Background: The mathematical operation of logarithm data follows the rules of logarithm as the numbers relate to specific meanings. The numbers prior to the decimal are the mantissa or the transformed power of 10 and the numbers after the decimal are the
Suthon Vongsheree
doaj  

Solution to an open problem on a logarithmic integral and derived results

open access: yesAnnals of the West University of Timisoara: Mathematics and Computer Science
This article solves an open problem that was previously stated by providing an exact evaluation of a logarithmic integral. Furthermore, the result is generalized by introducing a new adjustable parameter.
Coine Clément, Chesneau Christophe
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Logarithm of the Discrete Fourier Transform

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2007
The discrete Fourier transform defines a unitary matrix operator. The logarithm of this operator is computed, along with the projection maps onto its eigenspaces. A geometric interpretation of the discrete Fourier transform is also given.
Michael Aristidou, Jason Hanson
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Exponential and logarithm of multivector in low-dimensional (n = p + q < 3) Clifford algebras

open access: yesNonlinear Analysis, 2022
The aim of the paper is to give a uniform picture of complex, hyperbolic, and quaternion algebras from a perspective of the applied Clifford geometric algebra.
Adolfas Dargys, Artūras Acus
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

An explicit formula for the matrix logarithm

open access: yesAfrican Vision and Eye Health, 2005
No Abstract ...
João R Cardoso
doaj   +1 more source

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