Results 51 to 60 of about 144,366 (260)
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Log-PF: Particle Filtering in Logarithm Domain
This paper presents a particle filter, called Log-PF, based on particle weights represented on a logarithmic scale. In practical systems, particle weights may approach numbers close to zero which can cause numerical problems.
Christian Gentner +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Leading Logarithm Quantum Gravity
The continual production of long wavelength gravitons during primordial inflation endows graviton loop corrections with secular growth factors. During a prolonged period of inflation, these factors eventually overwhelm the small loop-counting parameter ...
S. P. Miao, N. C. Tsamis, R. P. Woodard
doaj +1 more source
A NEW PROPOSED METHOD FOR SOLVING AN ELLIPTIC CURVE DISCRETE LOGARITHM PROBLEM
In this work, we present a new approach for solving Elliptic Curve Discrete Logarithm Problem. This method provides a new access to the field of attacking methods the Elliptic Curve Cryptosystems.
Ammar Ali Neamah
doaj +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
APLIKASI DISTRIBUSI DERET PANGKAT PADA BEBERAPA JENIS DISTRIBUSI KHUSUS
This research about the definition and theorem of power series distribution according to its analitycal characteristics. Then it discusse about the application to another distribution, and discusse about the relation between it, but it especially ...
Mozart Winston Talakua
doaj +1 more source
Background Diabetic nephropathy, a major complication of diabetes, is the primary risk factor for dialysis, cardiovascular diseases, and mortality. Dietary fatty acids (FAs) have been revealed to be related with cardiovascular diseases in the general ...
Takuro Okamura +11 more
doaj +1 more source
We construct a proper moduli space which is a Deligne-Mumford stack parametrising quasimaps relative to a simple normal crossings divisor in any genus using logarithmic geometry. We show this moduli space admits a virtual fundamental class of the expected dimension leading to numerical invariants which agree with the theory of Battistella-Nabijou where
openaire +3 more sources
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

