Results 211 to 220 of about 51,196 (253)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Endogenous precision of the number sense. [PDF]

Elife
Prat-Carrabin A, Woodford M.
europepmc   +1 more source

Fundamental Challenges, Physical Implementations, and Integration Strategies for Ising Machines in Large‐Scale Optimization Tasks

Advanced Electronic Materials, EarlyView.
Ising machines are emerging as specialized hardware solvers for computationally hard optimization problems. This review examines five major platforms—digital CMOS, analog CMOS, emerging devices, coherent optics, and quantum systems—highlighting physics‐rooted advantages and shared bottlenecks in scalability and connectivity.
Hyunjun Lee, Joon Pyo Kim, Sanghyeon Kim
wiley   +1 more source

Computational Study of the Reaction between Ethylene Glycol and the CH Radical: Competition between Carbon Addition and Dehydrogenation. [PDF]

J Phys Chem A
Alessandrini S, Ye H, Melosso M, Puzzarini C.   +3 more
europepmc   +1 more source

Near-infrared prediction of tannin content in walnut kernels using wavelet transform combined with interpretable machine learning models. [PDF]

Front Plant Sci
Xia Q, Luo L, Yerzati Y, Ahmed MM, Chen Y, Wang S, Qin J, Chen L, Jin Q, Guo Z, Zhang R.   +10 more
europepmc   +1 more source

Expression of GPR34 in microglia remains stable in human Alzheimer's disease. [PDF]

Acta Neuropathol
Seiffer S, Rotter J, Brendler J, Ricken A, Detzer Z, Braune M, Schöneberg T, Schulz A, Winter K, Bechmann I.   +9 more
europepmc   +1 more source

Minimizing interface defects and enhancing optical brightness of µLEDs through polymeric encapsulants. [PDF]

Commun Eng
Gavirneni PP, Wong WS.
europepmc   +1 more source

AS7341 Spectral Sensor with Machine Learning for Non-Contact Temperature Monitoring in Electrolytic-Plasma Hardening. [PDF]

Sensors (Basel)
Kussainov R, Erboluly A, Bakyt Z, Kadyrbolat N, Kurmangaliyev R, Rakhadilov B, Koc V, Rakhmetollayeva A, Satbayeva Z.   +8 more
europepmc   +1 more source