Results 131 to 140 of about 449,073 (289)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Satellite freeze forecast system. Operating/troubleshooting manual [PDF]

Examples of operational procedures are given to assist users of the satellites freeze forecasting system (SFFS) in logging in on to the computer, executing the programs in the menu, logging off the computer, and setting up the automatic system ...
Martsolf, J. D.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

The Economic and Environmental Effects of an EU Ban on Illegal Logging Imports. Insights from a CGE Assessment [PDF]

Illegal logging is widely recognized as a major economic problem and one of the causes of environmental degradation. Increasing awareness of its negative effects has fostered a wide range of proposals to combat it by major international conservation ...
Francesco Bosello, Ramiro Parrado, Renato Rosa   +2 more
core  

GUYAFOR: a network of research permanent plots of tropical forests in French Guiana [PDF]

, 2008
GUYAFOR, a network of forest research permanent plots, is dedicated to long term studies in forest dynamics and biodiversity. Forest plots have been established in French Guyana from the late 60's to recent years by Cirad, ONF and CNRS.
Baraloto, Christopher, Blanc, Lilian, Chave, Jérôme, Guitet, Stéphane, Jolivot, Audrey   +4 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Application of Semi-Permanently Installed Optical Fiber Outside the Tubing in Offshore Heavy Oil Steam Huff and Puff Thermal Recovery Blocks

Cejing jishu
In the heavy oil steam huff and puff thermal recovery blocks of Yuedong island, Liaohe oilfield, dynamic monitoring of production profiles in individual wells is required.
CHI Ming, CHEN Jianbo, WANG Haipeng, ZHAO Yun, WANG Guiyu, ZHAO Yungang, WANG Xiaolong, WANG Longxiang   +7 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Research on low productivity and logging evaluation of coalbed methane wells: a case study of the Baode block

Frontiers in Earth Science
In this work, we analyzed the causes of low productivity in coalbed methane (CBM) wells by considering the Baode block as a case study. In addition to investigating the reasons for low productivity in mature CBM wells, we developed logging interpretation
Jin-Hai Zhang, Zhen Li, Ying-Liang Li, Hong-Qiang Guo, Rui Hao, Yang Pei   +5 more
doaj   +1 more source