Results 171 to 180 of about 991,789 (292)

Bis-thiosemicarbazone functions as a selective chemosensor with the lowest LOD for Hg ions in water-rich medium: implications for on-site detection and logic gate experiments. [PDF]

RSC Adv
Sharma S, Patra N, Kaur N, Pati PK, Mandal S, Bharatam PV, Lobana TS.   +6 more
europepmc   +1 more source

HER2 and HLA-A*02 dual CAR-T cells utilize LOH in a NOT logic gate to address on-target off-tumor toxicity. [PDF]

J Immunother Cancer, 2023
Bassan D, Weinberger L, Yi J, Kim T, Weist MR, Adams GB, Foord O, Chaim N, Tabak S, Bujanover N, Lopesco Y, Vucci K, Schnair C, Levy-Knafo L, Kendall RL, Calzone FJ, Sharbi-Yunger A.   +16 more
europepmc   +1 more source

Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control

Advanced Science, EarlyView.
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang, Xiangyang Zhan, Jiexiang Zhang, Mingyue Tan, Chuanmin Chu, Guanqun Ju, Xinyu Zhai, Jianyi Gu, Huirong Zhu, Dongliang Xu   +9 more
wiley   +1 more source

AND Logic Gate-Based Dual-Specificity DNA Circuit for Isothermal HBV rcDNA Detection. [PDF]

JACS Au
Si J, Gao Y, Yang Z, Liu G, Shen X, Yao Q, Zhu C.   +6 more
europepmc   +1 more source

An "AND" Molecular Logic Gate as a Super-Enhancers for De Novo Designing Activatable Probe and Its Application in Atherosclerosis Imaging. [PDF]

Adv Sci (Weinh), 2023
Sang M, Huang Y, Wang L, Chen L, Nawsherwan, Li G, Wang Y, Yu X, Dai C, Zheng J.   +9 more
europepmc   +1 more source

Receptogenesis in a Vascularized Robotic Embodiment

Advanced Science, EarlyView.
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov, Leonid Zinatullin, Hans Priks, Adele Metsniit, Urmas Johanson, Tarmo Tamm, Alvo Aabloo, Edoardo Sinibaldi, Indrek Must   +8 more
wiley   +1 more source

Triply Responsive Control of Ion Transport with an Artificial Channel Creates a Switchable AND to OR Logic Gate. [PDF]

Angew Chem Int Ed Engl
Malla JA, Fenton KJ, Bellamkonda A, Fidler SI, Wallace MI, McTernan CT.   +5 more
europepmc   +1 more source

Development of dual enzyme responsive molecular AND logic gate. [PDF]

Turk J Chem, 2022
Erbaş Çakmak S.
europepmc   +1 more source

Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation

Advanced Science, EarlyView.
A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source