Results 41 to 50 of about 7,233 (199)

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

A Galois connection between classical and intuitionistic logics. I: Syntax

, 2017
In a 1985 commentary to his collected works, Kolmogorov remarked that his 1932 paper "was written in hope that with time, the logic of solution of problems [i.e., intuitionistic logic] will become a permanent part of a [standard] course of logic.
Melikhov, Sergey A.
core  

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery

Advanced Science, EarlyView.
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo, Iwona Bernacka‐Wojcik, Lingkai Zhu, Marle E. J. Vleugels, Moa E. Hörberg, Caroline Lindholm, Magnus Berggren, Daniel T. Simon, Theresia Arbring Sjöström   +8 more
wiley   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, EarlyView.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Update rules and semantic universals. [PDF]

Linguist Philos, 2023
Incurvati L, Sbardolini G.
europepmc   +1 more source

A Galois connection between classical and intuitionistic logics. II: Semantics

, 2018
Three classes of models of QHC, the joint logic of problems and propositions, are constructed, including a class of subset/sheaf-valued models that is related to solutions of some actual problems (such as solutions of algebraic equations) and combines ...
Melikhov, Sergey A.
core  

Changing a semantics: opportunism or courage?

, 2014
The generalized models for higher-order logics introduced by Leon Henkin, and their multiple offspring over the years, have become a standard tool in many areas of logic.
A. Chagrov, A. Gil-Luezas, A. Mann, A. Mostowski, A. Pasztor, B. Davey, B. Ganter, B. Jónsson, B. ten Cate, D. Cantone, D. Gallin, D. Harel, D. Hilbert, D. Kozen, E. Bishop, E. Lopez-Escobar, G. Bezhanishvili, G. Sambin, H. Andréka, H. Andréka, H. Andréka, H. Andréka, H. Enderton, H.-D. Ebbinghaus, H.A. Priestley, H.A. Priestley, I. Walukiewicz, J. Akkanen, J. Barwise, J. Barwise, J. Barwise, J. Benthem van, J. Benthem van, J. Benthem van, J. Benthem van, J. Benthem van, J. Benthem van, J. Benthem van, J. Hintikka, J. Madarász, J. Väänänen, J. Väänänen, J. Väänänen, K. Kunen, L. Csirmaz, L. Esakia, L. Henkin, L. Henkin, L. Henkin, L. Henkin, L. Henkin, L. Henkin, L. Henkin, L. Henkin, L. Humberstone, L. Santocanale, L. Santocanale, M. Dunn, M. Dunn, M. Gehrke, M. Kracht, M. Manzano, M. Manzano, M.O. Rabin, N. Bezhanishvili, N. Bezhanishvili, N. Galatos, P. Blackburn, P. Hájek, R. Kaye, R. Montague, R.L. Vaught, S. Ambler, S. Feferman, S. Simpson, S.K. Thomason, T. Gergely, T. Hyttinen, V. Marra, V. Stebletsova, W. Blok, W. Holliday, W. Walkoe, Y. Venema, Y. Venema   +84 more
core   +1 more source

CRISPR/Cas13a: Compensatory Target Activation Mechanism

Advanced Science, EarlyView.
CRISPR/Cas13a‐CTAM as a novel compensatory target activation mechanism that enables synergistic activation of Cas13a via two independently editable short RNA effectors. This dual‐effector system maintains enzymatic activity comparable to traditional single‐effector while significantly enhancing flexibility, sensitivity, and application scope.
Bowen Jiang, Tenghua Zhang, Yao Lu, Shujun Zhou, Wenjing Xiao, Shuming Pan, Nan Shi, Yan Sheng, Jiaming Hu   +8 more
wiley   +1 more source