Results 171 to 180 of about 29,405 (206)

Problem driven innovation design strategies research for product manufacturing process. [PDF]

Sci Rep
Zhao Q, Wang H, Guo X, Zhang Q, Zeng H, Li X, Zhang K.   +6 more
europepmc   +1 more source

RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming

Angewandte Chemie, EarlyView.
RATEX integrated ribosome‐mediated transcription control with synthetic RNA regulators, enabling simultaneous processing of RNA, metabolite, and small‐molecule inputs through complex logic operations within a single transcript. The platform achieves up to 1,492‐fold gene regulation, multi‐input hybrid logic gates, RNA‐programmed signaling cascades, and
Hyunseop Goh, Hansol Kang, Chaeri Kim, Jongmin Kim   +3 more
wiley   +1 more source

Low Antibody Dosing in Cancer Therapy: Targeted Cytotoxicity Combined with Anti-Tumour Immunostimulation. [PDF]

Int J Mol Sci
Seledtsov VI, Seledtsova GV, Darinskas A, von Delwig A.   +3 more
europepmc   +1 more source

The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications

Angewandte Chemie, EarlyView.
This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec, Josef Holub, Maksim A. Samsonov, Zdeňka Růžičková, Josef Cvačka, Ján Vančo, Zdeněk Trávníček, Jan Belza, Zdeněk Dvořák, Jan Vrána, Aleš Růžička   +10 more
wiley   +1 more source

Automated annotation of complex natural products using a modular fragmentation-based structure assembly (MFSA) strategy. [PDF]

Sci Adv
Zhang M, Otsuki K, Tan L, Kikuchi T, Li N, Li W.   +5 more
europepmc   +1 more source

ACGA a Novel Biomimetic Hybrid Optimisation Algorithm Based on a HP Protein Visualizer: An Interpretable Web-Based Tool for 3D Protein Folding Based on the Hydrophobic-Polar Model. [PDF]

Biomimetics (Basel)
Sima I, Cristea DM, Iantovics LB, Niculescu V.   +3 more
europepmc   +1 more source

SynNotch CAR-T cell, when synthetic biology and immunology meet again. [PDF]

Front Immunol
Shirzadian M, Moori S, Rabbani R, Rahbarizadeh F.   +3 more
europepmc   +1 more source

Targeting copper death-related long non-coding RNAs: a novel strategy to overcome immunotherapy resistance in liver cancer. [PDF]

Front Immunol
Sheng X, Mi C, Shi G, Wang L, Li Y, Wang D, Wang W, Du Y, Wang S, Yang H.   +9 more
europepmc   +1 more source

Performance Guarantees of Recurrent Neural Networks for the Subset Sum Problem. [PDF]

Biomimetics (Basel)
Wang Z, Liao W, Jin Y, Wang Z.
europepmc   +1 more source

Study on design and practice of PBL teaching model based on STEM education concept. [PDF]

Sci Rep
Liu Z.
europepmc   +1 more source