Results 291 to 300 of about 23,446,041 (341)

Blood Biomarker‐Based Predictive Indicator for Liver Metastasis in Alpha‐Fetoprotein‐Producing Gastric Cancer and Multi‐Omics Tumor Microenvironment Insights

open access: yesAdvanced Science, EarlyView.
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding   +26 more
wiley   +1 more source

Vertically Aligned Carbon Nanotube Mechano‐Electrochemical Generator for Ultralow‐Frequency Ocean Wave Monitoring

open access: yesAdvanced Science, EarlyView.
A mechano‐electrochemical generator is proposed that harvests energy from ultralow‐frequency waves below 0.01 Hz for self‐powered disaster monitoring. The generator minimizes signal distortion, enabling precise measurement of subtle waves with overlapping frequencies.
Hyeon Jun Sim   +10 more
wiley   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

open access: yesAdvanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie   +9 more
wiley   +1 more source

Ultra‐Stable and Highly Luminescent Perovskite for Multi‐Color Ultraviolet Single‐Pixel Imaging

open access: yesAdvanced Science, EarlyView.
In this work, a novel strategy is presented for co‐passivation of perovskites via Mg2+ and SEBS, achieving high PLQY and enhanced stability in perovskite films, utilizing Fourier compressed sensing technology, integrated with single‐pixel imaging technology for UV detection and imaging.
Bin Xu   +9 more
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Logarithmic Helical Design for Reversed Magnetic Field in Magnetoelastic Soft Matters with Giant Current Outputs

open access: yesAdvanced Science, EarlyView.
According to literatures, magnetoelastic soft materials have achieved a maximum magnetic flux change of 80%, making it difficult to enhance the magnetic flux change. To address this, this manuscript proposed a reversed magnetic field strategy in conjunction with logarithmic helical design and magnetoelastic deformation.
Xiaojun Chen   +11 more
wiley   +1 more source

Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications

open access: yesAdvanced Electronic Materials, EarlyView.
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster   +2 more
wiley   +1 more source

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