Results 191 to 200 of about 2,017,337 (259)

Categorical Data Analysis - Logistic Regression

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2014
Shengping Yang, Gilbert Berdine
doaj  

Utilizing Causal Network Markers to Identify Tipping Points ahead of Critical Transition

open access: yesAdvanced Science, EarlyView.
The study proposes a causal network markers (CNMs) framework to identify early‐warning signals preceding critical transitions. It validates CNMs on various computational benchmark models and real‐world datasets, demonstrating higher accuracy and flexibility compared to existing approaches.
Shirui Bian   +4 more
wiley   +1 more source

RAD21L1 Is Sufficient and Effective for Reprogramming Human Sertoli Cells to Phenotypic Spermatogonial Stem Cells Through DNA Methylation and Essential for Male Fertility

open access: yesAdvanced Science, EarlyView.
RAD21L1 is upregulated in human Sertoli cells to be transited to become spermatogonial stem cells by overexpressing DAZ family three genes. RAD21L1 is sufficient and effective for reprogramming Sertoli cells into human spermatogonial stem cells with high safety through DNA methylation.
Caimei He   +4 more
wiley   +1 more source

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

open access: yesAdvanced Science, EarlyView.
Despite its canonical role in inhibiting DNA synthesis, GGH promotes tumor growth as a novel RNA‐binding protein. GGH binds GC‐rich 5′UTRs (e.g., CDC6/CCND1), recruits HuR to form a ternary complex that stabilizes mRNA via circular conformation, fueling DNA replication and the cell cycle. Targeting this axis suppresses NSCLC progression.
Yu Li   +9 more
wiley   +1 more source

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