Results 241 to 250 of about 2,017,337 (259)

Ascites complications risk factors of decompensated cirrhosis patients: logistic regression and prediction model. [PDF]

BMC Gastroenterol
Zheng X, Wei W.
europepmc   +1 more source

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu, Peng Zheng, Yunxiao Xiao, Qianheng Wang, Xin Pan, Xiaoqi Zhou, Yibing Lv, Junyi Xiao, Yong He, Tao Huang, Ping Lei   +10 more
wiley   +1 more source

Prediction of future aging-related slow gait and its determinants with deep learning and logistic regression. [PDF]

PLoS One
Deatsch A, McKenna M, Palumbo J, Tian Q, Simonsick E, Ferrucci L, Jeraj R, Spencer RG.   +7 more
europepmc   +1 more source

GLM7 – A Novel Composite Glycolipid Index Derived from Routine Health Indicators for Enhanced Diagnosis and Prediction of Multimorbidity

Advanced Science, EarlyView.
This study leverages NHANES data to analyze 49 routine indicators, identifying the top 10 diagnostic markers for five major diseases and introducing GLM7, a novel indicator. Restricted cubic spline analyses, forest plot evaluations, and XGBoost modeling demonstrate conventional indicators' efficacy and GLM7's value for disease diagnosis/prediction ...
Zhihua Wang, Shuo Chen, Xiaojun Feng, Xi Chen, Paul C Evans, Hans Strijdom, Yu Ding, Jianping Weng, Suowen Xu   +8 more
wiley   +1 more source

Comparative performance of logistic regression, multilayer perceptron and decision tree models for predicting surgical pressure injuries: a retrospective cohort study. [PDF]

BMJ Health Care Inform
Li CY, Chu CM, Chen CW, Ke HY, Hsiao PC, Pan HH.   +5 more
europepmc   +1 more source

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Ultrasound radiomics-based logistic regression model for fibrotic NASH. [PDF]

BMC Gastroenterol
Xia F, Wei W, Wang J, Wang Y, Wang K, Zhang C, Zhu Q.   +6 more
europepmc   +1 more source

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

Advanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu, Benjie Xu, Rui Hu, Bo Yang, Peipei Shen, Yu Xu, Xiaojun Zhang, Danqi Qian, Gang Wu, Shengjun Ji, Yutian Zhao, Ke Gu   +11 more
wiley   +1 more source

Risk factors associated with severe progression of Parkinson's disease: random forest and logistic regression models. [PDF]

Front Neurol
Tan J, Huang E, Hao Y, Wan H, Zhang Q.
europepmc   +1 more source