Results 61 to 70 of about 420,344 (305)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Logistics Network Construction of Hazardous Goods Based on Analytic Hierarchy Process
Chemical Engineering Transactions, 2016 Chemical hazardous goods logistics has become a new branch of logistics, but how to choose the location of logistics center and build the logistics network is still an urgent problem to be solved by logistics enterprise. Based on this, this paper studies
X.L. Tang
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Outsourcing and performance of inbound logistics for the automobile industry [PDF]
Journal of International Logistics and Trade, 2007 The studies focusing on inbound logistics in the automobile industry have been limited because of the relatively small portion of logistics cost. But now it is recognized as one of the critical factors for efficient execution of supply chain management ...
Myoung-Kang Heo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
The Role of Logistics Centres in the Region Development [PDF]
, 2016 The article focuses on the role of logistic centers in the environment of economic regionalization. The discussion indicates that logistics centers built in a particular area, create a specific economic climate which allows to consider them as a regional
Witczyńska, Katarzyna Barbara; The International University of Logistics and Transport in Wroclaw
core
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
The Impact of logistics management on logistics performance in Jordan: The moderating effect of competitive advantage [PDF]
Journal of Project ManagementThis research is aimed at analyzing how the logistics management practices (LMP) influence the logistics performance (LP) in logistics efficiency and logistics effectiveness.
Thabet Banihani
doaj +1 more source
Towards Improved Data Quality Management Tools in Logistics [PDF]
In today’s logistics environment, high-quality data is essential for ensuring efficient processes and sustaining competitiveness. However, missing, erroneous, or duplicate entries in master data often lead to significant business consequences, such as ...
Tebernum, Daniel +3 more
core +1 more source