Results 271 to 280 of about 11,127,235 (334)

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

Advanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang, Yang Hu, Feiyu Wang, Xintao Peng, Honggang Qi, Yuanyuan Yao, Canyu Zhang, Lijie Zhou, Xuemei Liang, Kang Xu, Cong Zhang, Aifeng Zhang, Chen Chen, Yu Zeng, Chenchen Zhang, Guangming Gan, Xinjian Zhu   +16 more
wiley   +1 more source

Evaluation of the National Immunization Program in a city in the interior of Pernambuco in the light of Donabedian's triad. [PDF]

Aten Primaria
da Rocha MFN, Lopes MVP, Pereira JCN, Montenegro SMSL.   +3 more
europepmc   +1 more source

Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects

Advanced Science, EarlyView.
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su, Jian Qin, Hui Shen, Ling‐Li Zeng, Baojuan Li, Jin Liu, Xuemei Song, Li Liu, Weidan Pu, Tongjian Bai, Huaning Wang, Hong Yin, Kai Wang, Lingjiang Li, Dewen Hu   +14 more
wiley   +1 more source

Investment feasibility and optimization strategies of RFID technology in logistics field. [PDF]

Sci Rep
Han J, Ai H, Li R, Deng X, Wu Y, Wang J, Wei Z.   +6 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

A multi-objective optimization framework integrating ICSL deep learning for forecasting and scheduling emergency medical supply demand in public health emergencies. [PDF]

Sci Rep
Pang Y, Zhou S, Lou B, Xiong H, Fan K, Ning L, Pan Y, Gu G, Wang X, Zhou D, Bao C.   +10 more
europepmc   +1 more source

Συμβάσεις Performance Based Logistics

, 2013
openaire   +1 more source

Diagnostic Value of 18F-FDG PET/CT Parameters Combined with Serum FOXM1 for Lymph Node Metastasis in Colorectal Cancer. [PDF]

Clin Interv Aging
Zhu Y, Bo L, Li L, Sun Y, Wu B.
europepmc   +1 more source

Optimizing urban last mile delivery efficiency through dynamic vehicle routing heuristics and traffic flow analysis. [PDF]

Sci Rep
Liu L, Wang T.
europepmc   +1 more source

GNN-RMNet: Leveraging graph neural networks and GPS analytics for driver behavior and route optimization in logistics. [PDF]

PLoS One
Aldhahri EA, Almazroi AA, Alkinani MH, Alqarni M, Alghamdi EA, Ayub N.   +5 more
europepmc   +1 more source