Results 71 to 80 of about 11,127,235 (334)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Evaluating the Effects of Digital Transformation on Logistics Performance: A Large-Scale Perspective on Industrial Competitiveness

Journal of Eta Maritime Science
While digital technologies continue to change various industries, many sectors are adopting digital transformation, including logistics, which is critical for the functioning of supply chains and the flow of international trade.
Duygu Şahan
doaj   +1 more source

Logistics outsourcing and performance of manufacturing small and medium-sized enterprises in Nairobi

The Southern African Journal of Entrepreneurship and Small Business Management, 2018
Background: Logistics outsourcing has been accepted as a strategy through which small and medium-sized enterprises (SMEs) can access the logistics capabilities they lack internally at a lower cost.
Joash Mageto, Gerrie Prinsloo, Rose Luke
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

LOGISTICS PERFORMANCE INDEX IN INTERNATIONAL TRADE: CASE OF CENTRAL AND EASTERN EUROPEAN AND WESTERN BALKANS COUNTRIES

, 2020
The volume of international trade heavily depends on factors facilitating trade and contributing to reducing its costs. The importance of international logistics as trade facilitator is increasingly emphasised in the literature.
Filip Ž. Bugarčić, Viktorija Skvarciany, Nemanja Stanišić   +2 more
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

A decision support model for identification and prioritization of key performance indicators in the logistics industry [PDF]

, 2016
YesPerformance measurement of logistics companies is based upon various performance indicators. Yet, in the logistics industry, there are several vaguenesses, such as deciding on key indicators and determining interrelationships between performance ...
Aktas, Aktas, Akyuz, Atafar, Berk Kucukaltan, Beynon, Bhagwat, Björklund, Büyüközkan, Chang, Chia, Chia, Chow, Choy, Colicchia, Couger, De Felice, Donaldson, Emel Aktas, Forslund, Freeman, Freeman, Garengo, Gasiea, Ghauri, Gopal, Grant, Grosswiele, Gunasekaran, Gunasekaran, Gunasekaran, Gunasekaran, Gutierrez, Hair, Hair, Handfield, Horenbeek, Hsu, Huang, Hubbard, Jothimani, Kaplan, Kaplan, Karpak, Kayakutlu, Keebler, Kladogeni, Küçükaltan, Lambert, Lee, Lee, Leung, Lieb, Lin, Liou, Liu, Liu, Marasco, McLachlin, Meade, Meade, Michaelidou, Min, Mishra, Nair, Neely, Poveda-Bautista, Poveda-Bautista, Qureshi, Rajesh, Ravi, Saaty, Saaty, Saaty, Saaty, Saaty, Saaty, Saaty, Shaik, Shaik, Shaik, Shaw, Stank, Stephen, Striteska, Thakkar, Tjader, Tsai, Tzeng, Velasquez, Vondey, Wang, Wang, Wong, Wu, Wu, Wu, Yang, Yeap, Yurdakul, Zahir Irani, Zang, Öztayşi   +102 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Beyond Average Effects: Performance-Dependent Logistics Challenges in Emerging Asian Transportation Trade

Logistics
Background: Emerging Asian economies face a critical policy dilemma: macroeconomic and sustainability factors affect high-performing and struggling logistics exporters in fundamentally different ways.
Audai Al-Majali, Ahmad Alsarayreh, Huthaifa Alqaralleh   +2 more
doaj   +1 more source