Results 71 to 80 of about 21,980,265 (388)

A Patient‐Derived Organ‐on‐Chip Platform for Modeling the Tumor Microenvironment and Drug Responses in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan   +11 more
wiley   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

open access: yesAdvanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang   +8 more
wiley   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

open access: yesAdvanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou   +14 more
wiley   +1 more source

Modelación del riesgo de insolvencia en empresas del sector salud empleando modelos logit || Modeling of Insolvency Risk in Health Sector Companies Using Logit Models

open access: yesRevista de Métodos Cuantitativos para la Economía y la Empresa, 2018
Este artículo muestra la predicción del nivel de insolvencia en empresas que no cotizan en bolsa y pertenecen al sector salud con uno y dos años de anticipación, utilizando el análisis de regresión logística múltiple basado en indicadores de liquidez ...
Támara Ayús, Armando Lenin   +3 more
doaj  

Safety ramifications of a change in pedestrian crosswalk law: A case study of Oregon, USA

open access: yesInternational Journal of Transportation Science and Technology, 2019
Pedestrians are some of the most vulnerable road users as they are not protected by safety devices, and must also share the road with vehicles traveling at dangerous speeds, particularly during road crossings.
Yue Ke, Konstantina Gkritza
doaj   +1 more source

Categorical Data [PDF]

open access: yes
A very brief survey of regression for categorical data. Categorical outcome (or discrete outcome or qualitative response) regression models are models for a discrete dependent variable recording in which of two or more categories an outcome of interest ...
A. Colin Cameron
core  

Parameter estimation in multivariate logit models with many binary choices

open access: yes, 2014
Multivariate Logit models are convenient to describe multivariate correlated binary choices as they provide closed-form likelihood functions. However, the computation time required for calculating choice probabilities increases exponentially with the ...
K. Bel, D. Fok, R. Paap
semanticscholar   +1 more source

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

open access: yesAdvanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan   +21 more
wiley   +1 more source

Wage Adjustment Practices and the Link between Price and Wages: Survey Evidence from Colombian Firms *

open access: yesLecturas de Economía, 2012
This paper explores firms’ wage adjustment practices in the Colombian formal labor market; specifically, the timing and frequency of wage increases, as well as the link between wage and price changes.
Ana Iregui, Ligia Melo, María Ramírez
doaj  

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