Results 71 to 80 of about 4,474,661 (295)
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub +3 more
wiley +1 more source
On the Shifted Hybrid Log-Normal Distribution
StatisticaThe log-normal distribution is widely used to model positive valued data in many areas of applied research. However, sometimes the log-normal distribution does not completely satisfy the fitting expectations in every real life situations.
Damodaran Santhamani Shibu +2 more
doaj +1 more source
Lognormal and Pareto distributions in the Internet [PDF]
Computer Communications, 2005 Numerous studies have reported long-tailed distributions for various network metrics, including file sizes, transfer times, and burst lengths. We review techniques for identifying long-tailed distributions based on a sample, propose a new technique, and apply these methods to datasets used in previous reports.
openaire +1 more source
Control Charts for the Lognormal Distribution [PDF]
Control Charts are the main tools of Statistical Process Control. They are used for deciding whether a process is statistically stable or not. Much theory and many applications have been developed for the Gaussian (Normal) distribution in this area ...
Panaretos, John +2 more
core
Parameters of lognormal contrast distribution.
, 2014 Parameters of the lognormal distributions of the r.m.s. contrasts of our database. μ is the expected value, σ2 the variance of the distribution; both parameters were obtained by a lognormal fit to the distribution. n is the number of elements.
Jens Peter Lindemann (111) +2 more
core +1 more source
Canadian Journal of Statistics, EarlyView.Abstract This article presents a strategy for conducting regression analysis of zero‐truncated recurrent event data. The research is partly motivated by a pediatric mental health care (PMHC) program based on administrative data. We are particularly interested in how the occurrence of an event depends on its past occurrences and the associated ...
Anqi A. Chen +3 more
wiley +1 more source
Bayes reliability measures of Lognormal and inverse Gaussian distributions under ML-II ε-contaminated class of prior distributions [PDF]
In this paper we employ ML-II ε-contaminated class of priors to study the sensitivity of Bayes Reliability measures for an Inverse Gaussian (IG) distribution and Lognormal (LN) distribution to misspecification in the prior.
Sinha, Pankaj, Jayaraman, Prabha
core
Clinical Pharmacology &Therapeutics, EarlyView.Cofetuzumab pelidotin (Cofe‐P) is an anti‐protein tyrosine kinase 7 (PTK7) antibody‐drug conjugate (ADC) being investigated for the treatment of adults with PTK7‐expressing, recurrent non‐small cell lung cancer (NSCLC). The first‐in‐human (FIH) trial demonstrated tolerability of dosages ≤ 2.8 mg/kg once every 3 weeks (Q3W) and ≤ 3.2 mg/kg Q2W ...
Carla Biesdorf +8 more
wiley +1 more source
Inference for double Pareto lognormal queues with applications [PDF]
In this article we describe a method for carrying out Bayesian inference for the double Pareto lognormal (dPlN) distribution which has recently been proposed as a model for heavy-tailed phenomena. We apply our approach to inference for the dPlN/M/1 and M/
Michael P. Wiper +3 more
core
Clinical Pharmacology &Therapeutics, EarlyView.Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke +12 more
wiley +1 more source