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Bridging the Intellectualist Divide: A Reading of Stanley’s Ryle [PDF]

open access: yes, 2019
Gilbert Ryle famously denied that knowledge-how is a species of knowledge-that, a thesis that has been contested by so-called “intellectualists.” I begin by proposing a rearrangement of some of the concepts of this debate, and then I focus on Jason ...
Navarro Reyes, Jesús
core   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

open access: yesAdvanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu   +6 more
wiley   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

open access: yesAdvanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li   +11 more
wiley   +1 more source

Logos endiathetos e logos prophorikos

open access: yes, 2023
I return here, for certain points, to the distinction between λόγος ἐνδιάθετος and λόγος προφορικός which is often rendered by the opposition between inner and outer speech. If, as an important testimony of Sextus Empiricus shows, the λόγος ἐνδιάθετος is, for the Stoics, related to the μετάβασις which allows one to grasp the logical connections ...
openaire   +1 more source

Logos

open access: yesWriting across the University of Alberta, 2023
Rhetorical appeals such as ethos, pathos, and logos are foundational concepts in Writing Studies courses. For this reason, we were delighted to read this succinct and insightful piece by Feisal Sharif about the appeal of logos. Feisal submitted this piece for a first-year Writing Studies course.
openaire   +1 more source

Consumer perception of different organic certification schemes in five European countries [PDF]

open access: yes, 2011
With the introduction of the new mandatory EU logo for organic food and farming, the various existing organic certification schemes in the European market face a challenge: Producers and retailers might only continue to display the existing organic logos
Hamm, Ulrich, Janssen, Meike
core  

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

open access: yesAdvanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang   +11 more
wiley   +1 more source

The Prima Facie View of Perceptual Imagination

open access: yesErgo, An Open Access Journal of Philosophy
Perception is said to have assertoric force: It inclines the perceiver to believe its content. In contrast, perceptual imagination is commonly taken to be non-assertoric: Imagining winning a piano contest does not incline the imaginer to believe they ...
Andrea Rivadulla-Duró
doaj   +2 more sources

IgG‐Bridging–Seeded Synergistic Aggregation of SARS‐CoV‐2 Spikes Underlies Potent Neutralization by a Low‐Affinity Antibody

open access: yesAdvanced Science, EarlyView.
Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv   +29 more
wiley   +1 more source

Retailer-Wholesaler Response to State-Sponsored Marketing Programs: The Case of Jersey Fresh [PDF]

open access: yes
Jersey Fresh retailers and wholesalers feel that the logos are effective in increasing sales. Most feel that the popularity of the logo among the consumers is moderate.
Govindasamy, Ramu   +3 more
core   +1 more source

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