Results 101 to 110 of about 676,310 (346)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Wood decomposition activity of oyster mushroom (Pleurotus ostreatus) isolate in situ

open access: yesJournal of Forest Science, 2013
The purpose of the research was to examine the decomposition rate of beech (Fagus sylvatica) and aspen (Populus tremula) logs after an oyster mushroom (Pleurotus ostreatus) infection as well as the effect of fruit body formation on the chemical ...
M. Pavlík, Š. Pavlík
doaj   +1 more source

Data Cleaning Methods for Client and Proxy Logs [PDF]

open access: yes, 2006
In this paper we present our experiences with the cleaning of Web client and proxy usage logs, based on a long-term browsing study with 25 participants. A detailed clickstream log, recorded using a Web intermediary, was combined with a second log of user
Herder, E., Obendorf, H., Weinreich, H.
core   +2 more sources

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Secure management of logs in internet of things [PDF]

open access: yes, 2015
Ever since the advent of computing, managing data has been of extreme importance. With innumerable devices getting added to network infrastructure, there has been a proportionate increase in the data which needs to be stored.
Gupta, Udit
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner   +6 more
wiley   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

KERENTANAN BEBERAPA JENIS KAYU TERHADAP SERANGAN KUMBANG AMBROSIA

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
Ambrosia  beetles  belong to the most destructive wood borers  that attack fresh cut logs. To determine the damage of some wood species caused by the pests, a field study was conducted by calculating the intensity  of the beetle infestation on the ...
Paimin Sukartana
doaj   +1 more source

The American put is log-concave in the log-price

open access: yesJournal of Mathematical Analysis and Applications, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Erik Ekström, Johan Tysk
openaire   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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