Results 101 to 110 of about 699,238 (343)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Graph-based discovery of ontology change patterns [PDF]
, 2011 Ontologies can support a variety of purposes, ranging from capturing conceptual knowledge to the organisation of digital content and information. However, information systems are always subject to change and ontology change management can pose challenges.
Abgaz, Yalemisew +2 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
KERENTANAN BEBERAPA JENIS KAYU TERHADAP SERANGAN KUMBANG AMBROSIA
Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017 Ambrosia beetles belong to the most destructive wood borers that attack fresh cut logs. To determine the damage of some wood species caused by the pests, a field study was conducted by calculating the intensity of the beetle infestation on the ...
Paimin Sukartana
doaj +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
PENGAWASAN ADMINISTRATIF TATA USAHA KAYU DI TPK DAN LOGPOND HPH DENGAN PROGRAM KOMPUTER
Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017 Ministry of forestry requires the forest concession holders to fill in logs administrative forms containing log records to supervise logs production and circulation in forest concessions.
Hariyatno Dwiprabowo
doaj +1 more source
Singular Log Structures and Log Crepant Log Resolutions I
We introduce a class of singular log schemes in three dimensions and conjecture that log schemes in this class admit log crepant log resolutions. We provide examples as evidence and relate this conjecture to the conjecture made in [4] and the Gross--Siebert program.
Corti, Alessio +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source