Results 61 to 70 of about 676,310 (346)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

Deadwood Diversity of Boreal and Sub-boreal Old-growth Forests in Southern Finland

South-East European Forestry
In the last century, old-growth forests in boreal and sub-boreal zone have decreased, along with their contribution to biological diversity. In order to carry on management strategies aimed at maintaining deadwood diversity in old-growth forests, it is ...
Isabella De Meo, Roberta Pastorelli, Francesko Vitali, Alessandro Paletto   +3 more
doaj   +1 more source

Predicting total organic carbon from few well logs aided by well-log attributes

Petroleum, 2023
Derivative/volatility well-log attributes from very few commonly recorded well logs can assist in the prediction of total organic carbon (TOC) in shales and tight formations.
David A. Wood
doaj   +1 more source

The Sedentary Multi-Frequency Survey. I. Statistical Identification and Cosmological Properties of HBL BL Lacs [PDF]

, 1999
We have assembled a multi-frequency database by cross-correlating the NVSS catalog of radio sources with the RASSBSC list of soft X-ray sources, obtaining optical magnitude estimates from the Palomar and UK Schmidt surveys as provided by the APM and ...
Avni Y., Bade N., Blandford R. D., Browne I. W. A., Caccianiga A., Cao L., Cavaliere A., Ciliegi P., Condon J. J., Dickey J. M., Falomo R., Fischer J. U., Fossati G., Fossati G., Ghisellini G., Giommi P., Giommi P., Giommi P., Giommi P., Gregg M. D., Irwin M., Laurent-Muehleisen S., M. T. Menna, Morris S. L., P. Giommi, P. Padovani, Padovani P., Padovani P., Padovani P., Padovani P., Padovani P., Perlman E. S., Perlman E. S., Pian E., Rector T. A., Schmidt M., Stecker F. W., Stickel M., Stickel M., Stickel M., Stocke J. T., Stocke J. T., Urry C. M., Urry C. M., Voges W., White R. L., Wilkes B. J., Wolter A.   +47 more
core   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Case study of qualitative sorting of raw wood assortments in the conditions of a forestry enterprise in Slovakia

Central European Forestry Journal, 2022
Valuation of timber growing in commercial forests is a key issue for forest owners, forest enterprises, but also a starting point for long-term planning in the field of forest management.
Gejdoš Miloš, Gergeľ Tomáš
doaj   +1 more source

Description of the Larva of \u3ci\u3eDioedus Punctatus\u3c/i\u3e LeConte (Coleoptera: Tenebrionidae) [PDF]

, 2017
Larvae of Dioedus punctatus LeConte have been collected from logs, probably Ulmus americana, in the red-rotten stage of decay and determined from reared adults.
Young, Daniel K
core   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Predicting the value of grey alder (Alnus incana) logs based on external quality

Silva Fennica, 1999
The quality of grey alder logs (Alnus incana) was studied by sawing sample logs from two different forests in November 1995–February 1996. For grading of grey alder logs and sawn timber the proposed system of Keinänen and Tahvanainen (1995) plus the ...
Kärki, Timo
doaj   +1 more source

A layered framework for pattern-based ontology evolution [PDF]

, 2011
The challenge of ontology-driven modelling of information components is well known in both academia and industry. In this paper, we present a novel approach to deal with customisation and abstraction of ontology-based model evolution.
Abgaz, Yalemisew, Javed, Muhammad, Pahl, Claus   +2 more
core   +2 more sources