Results 71 to 80 of about 78,550 (264)
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Revista Fuentes El Reventón Energético, 2009 One of the main problems present in the hydrocarbon industry is the lack of available information necessary to conduct a detailed study of the characteristics of the subsoil, as is the sonic propagation speed, useful for calculating porosity, rock¿s ...
Andres Camilo Rincón Chávez +4 more
doaj
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
PENGAWASAN ADMINISTRATIF TATA USAHA KAYU DI TPK DAN LOGPOND HPH DENGAN PROGRAM KOMPUTER
Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017 Ministry of forestry requires the forest concession holders to fill in logs administrative forms containing log records to supervise logs production and circulation in forest concessions.
Hariyatno Dwiprabowo
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
KERENTANAN BEBERAPA JENIS KAYU TERHADAP SERANGAN KUMBANG AMBROSIA
Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017 Ambrosia beetles belong to the most destructive wood borers that attack fresh cut logs. To determine the damage of some wood species caused by the pests, a field study was conducted by calculating the intensity of the beetle infestation on the ...
Paimin Sukartana
doaj +1 more source
Singular Log Structures and Log Crepant Log Resolutions I
We introduce a class of singular log schemes in three dimensions and conjecture that log schemes in this class admit log crepant log resolutions. We provide examples as evidence and relate this conjecture to the conjecture made in [4] and the Gross--Siebert program.
Corti, Alessio +2 more
openaire +2 more sources