Results 31 to 40 of about 1,649 (190)

Bury my axe in wounded knee: A case of native knee septic arthritis caused by multidrug resistant Lomentospora prolificans [PDF]

Medical Mycology Case Reports
A 39-year-old male presenting with swelling and pain in the left knee after traumatic injury was diagnosed with rapidly progressive septic arthritis of the knee due to pan-resistant Lomentospora prolificans. While L. prolificans is an environmental mold,
Weston Carpenter, Catherine Pulaski, Alexander Hahn, Brenton Nash, Michael Sobieraj, Jeffrey Aeschlimann, Lisa M. Chirch   +6 more
doaj   +2 more sources

840 Limb Salvage After Lomentospora Osteomyelitis in a Burn-Injured Patient Treated with Fosmanogepix [PDF]

J Burn Care Res
Introduction Burn patients are highly susceptible to infections due to factors like loss of the protective skin barrier, immunosuppression, prolonged open wounds, mechanical ventilation and invasive lines.
Gelina M. Sani, Ian Powelson, Derek Bays, Sierra Young, Erin L. Louie, J. Heard   +5 more
europepmc   +2 more sources

Comparative Pathogenicity of Lomentospora prolificans (Scedosporium prolificans) Isolates from Mexican Patients [PDF]

Mycopathologia, 2017
We identified 11 Lomentospora prolificans isolates recovered from Mexican patients using phenotypic and molecular characteristics. The identification of isolates was assessed by internal transcribed spacer (ITS rDNA) sequencing. In vitro susceptibility
Ballesteros Elizondo, Raquel, Elizondo Zertuche, Mariana, Garza Veloz, Idalia, M. González, Gloria, M. Montoya, Alexandra, Robledo Lea, Efrén, Sánchez Núñez, Ana L.   +6 more
core   +3 more sources

Multisystem <i>Lomentospora prolificans</i> progression on fosmanogepix despite <i>in vitro</i> activity: a call for expanding clinical research on novel antifungals. [PDF]

ASM Case Rep
Background Lomentospora prolificans is a rare and often fatal cause of invasive mold disease (IMD), particularly in immunocompromised individuals. Treatment remains difficult due to intrinsic resistance to most antifungals and the challenges of achieving
Cooper RA, Arif S, Baker AW, Wiederhold NP, Sarantopoulos S, Iftikhar M, Stanly K, Collis B, Ni B, Sim BZ, Perfect JR, Alexander BD, Heldman MR.   +12 more
europepmc   +2 more sources

Disseminated <i>Lomentospora prolificans</i> infection in a patient with neutropenia treated with ipilimumab and nivolumab. [PDF]

BMJ Case Rep
Immune checkpoint inhibitor immunotherapy enhances T cell activity against cancer cells but often leads to the immune system targeting healthy cells, causing ‘immune-related adverse events’ (irAEs).
Dunstan NW, Robinson JO, Walczak A, Higgins A, Karthaus M, Ariyapperuma MH.   +5 more
europepmc   +2 more sources

Conidial germination in Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lomentospora prolificans: influence of growth conditions and antifungal susceptibility profiles [PDF]

Memorias do Instituto Oswaldo Cruz, 2016
In the present study, we have investigated some growth conditions capable of inducing the conidial germination in Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lomentospora prolificans.
Thaís Pereira de Mello, Ana Carolina Aor, Simone Santiago Carvalho de Oliveira, Marta Helena Branquinha, André Luis Souza dos Santos   +4 more
doaj   +2 more sources

New Insights Into The Melanin Structure Of Lomentospora prolificans

bioRxiv
Lomentospora prolificans is a filamentous fungus with a global distribution, manifesting particularly higher prevalence in human-impacted environments. This organism is associated with a wide spectrum of human infections, especially in immunosuppressed ...
Livia C Liporagi-Lopes, Christine Chrissian, Arlind Kacirani, E. Camacho, Ruth Stark, A. Casadevall   +5 more
semanticscholar   +3 more sources

Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients [PDF]

Pathogens, 2023
Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction.
Jesus E. Escamilla, Spenser E. January, Rodrigo Vazquez Guillamet   +2 more
doaj   +3 more sources

Repurposing of auranofin and honokiol as antifungals against Scedosporium species and the related fungus Lomentospora prolificans [PDF]

Virulence, 2021
The slowing-down de novo drug-discovery emphasized the importance of repurposing old drugs. This is particularly true when combating infections caused by therapy-refractory microorganisms, such as Scedosporium species and Lomentospora prolificans. Recent
Hajar Yaakoub, Cindy Staerck, Sara Mina, Charlotte Godon, Maxime Fleury, Jean-Philippe Bouchara, Alphonse Calenda   +6 more
doaj   +3 more sources

First Draft Genome Sequence of the Pathogenic Fungus Lomentospora prolificans (Formerly Scedosporium prolificans) [PDF]

G3: Genes, Genomes, Genetics, 2017
Here we describe the sequencing and assembly of the pathogenic fungus Lomentospora prolificans using a combination of short, highly accurate Illumina reads and additional coverage in very long Oxford Nanopore reads.
Ruibang Luo, Aleksey Zimin, Rachael Workman, Yunfan Fan, Geo Pertea, Nina Grossman, Maggie P. Wear, Bei Jia, Heather Miller, Arturo Casadevall, Winston Timp, Sean X. Zhang, Steven L. Salzberg   +12 more
doaj   +5 more sources