Investigation of a Lomentospora prolificans case cluster with whole genome sequencing [PDF]
Medical Mycology Case Reports, 2020 Lomentospora prolificans has caused outbreaks in immunocompromised patients. We performed whole genome sequencing (WGS) on 4 L. prolificans isolates from infections occurring during an 8-month period in the haematology unit at Hospital 1., and 2 isolates
Peter Boan +5 more
doaj +7 more sources
Disseminated Lomentospora prolificans infection presenting with arterial exsanguination [PDF]
Journal of Vascular Surgery Cases and Innovative Techniques, 2021 Lomentospora prolificans is an opportunistic fungal pathogen found especially in Australia, Spain, Portugal, California, and the southern United States. Although it causes a wide spectrum of infections, disseminated L.
Abdullah Nasif, MD +5 more
doaj +5 more sources
In Vitro Activity of the Novel Antifungal Olorofim against Scedosporium and Lomentospora prolificans [PDF]
Microbiology Spectrum, 2023 Scedosporium spp. and Lomentospora prolificans are an emerging group of fungi refractory to current antifungal treatments. These species largely affect immunocompromised individuals but can also be lung colonizers in cystic fibrosis patients.
Ourania Georgacopoulos +5 more
doaj +4 more sources
Repurposing of auranofin and honokiol as antifungals against Scedosporium species and the related fungus Lomentospora prolificans [PDF]
Virulence, 2021 The slowing-down de novo drug-discovery emphasized the importance of repurposing old drugs. This is particularly true when combating infections caused by therapy-refractory microorganisms, such as Scedosporium species and Lomentospora prolificans. Recent
Hajar Yaakoub +6 more
doaj +4 more sources
Glucosylceramides From Lomentospora prolificans Induce a Differential Production of Cytokines and Increases the Microbicidal Activity of Macrophages [PDF]
Frontiers in Microbiology, 2019 Lomentospora prolificans is an emerging opportunistic fungus with a high resistance to antifungal agents and it can cause localized infections in immunocompetent patients and disseminated infections with a high mortality rate in immunosuppressed patients.
Mariana Ingrid Dutra da Silva Xisto +8 more
doaj +9 more sources
In Vitro and In Vivo Effect of the Imidazole Luliconazole against Lomentospora prolificans and Scedosporium spp. [PDF]
Microbiology Spectrum, 2023 Infections with Scedosporium spp. and Lomentospora prolificans have become a serious threat in clinical settings. The high mortality rates associated with these infections can be correlated with their multidrug resistance.
Dan-Tiberiu Furnica +6 more
doaj +2 more sources
The Host Immune Response to Scedosporium/Lomentospora [PDF]
Journal of Fungi, 2021 Infections caused by the opportunistic pathogens Scedosporium/Lomentospora are on the rise. This causes problems in the clinic due to the difficulty in diagnosing and treating them.
Idoia Buldain +7 more
doaj +4 more sources
Case report: COVID-19-associated mucormycosis co-infection with Lomentospora prolificans: The first case and review on multiple fungal co-infections during COVID-19 pandemic [PDF]
Frontiers in Medicine, 2023 Along with the pandemic COVID-19 spreads, new clinical challenges have emerged in the health care settings, among which there is a high risk of secondary invasive fungal infections with significant mortality.
Mahzad Erami +10 more
doaj +2 more sources
ELISA Test for the Serological Detection of Scedosporium/Lomentospora in Cystic Fibrosis Patients [PDF]
Frontiers in Cellular and Infection Microbiology, 2020 The detection and diagnosis of the opportunistic fungi Scedosporium spp. and Lomentospora prolificans still relies mainly on low-sensitive culture-based methods.
Leire Martin-Souto +9 more
doaj +5 more sources
Lomentospora prolificans infective endocarditis and cerebral mycotic aneurysm [PDF]
Medical Mycology Case ReportsDisseminated Lomentospora prolificans infection typically occurs in immunocompromised hosts and is almost universally fatal. We describe a case of L.
Robert Hand +5 more
doaj +2 more sources