Results 51 to 60 of about 1,097 (151)

High risk of infection in ‘real‐world’ patients receiving ibrutinib, idelalisib or venetoclax for mature B‐cell leukaemia/lymphoma

European Journal of Haematology, Volume 110, Issue 5, Page 540-547, May 2023., 2023
Abstract Objective The infection risk in patients receiving ibrutinib, idelalisib or venetoclax for chronic lymphocytic leukaemia (CLL) or B‐cell lymphoma treated outside of clinical trials is incompletely defined. We sought to identify the severe infection rate and associated risk factors in a ‘real‐world’ cohort.
Amanda Tey, James Schwarer, Robert Raffa, Emily Shi, Eldho Paul, Stephen Opat, Claire Dendle, Jake Shortt   +7 more
wiley   +1 more source

Pathogen‐specific T Cells: Targeting Old Enemies and New Invaders in Transplantation and Beyond

HemaSphere, Volume 7, Issue 1, January 2023., 2023
Adoptive immunotherapy with virus‐specific cytotoxic T cells (VSTs) has evolved over the last three decades as a strategy to rapidly restore virus‐specific immunity to prevent or treat viral diseases after solid organ or allogeneic hematopoietic cell‐transplantation (allo‐HCT).
Anastasia Papadopoulou, Maria Alvanou, George Karavalakis, Ifigeneia Tzannou, Evangelia Yannaki   +4 more
wiley   +1 more source

Pulmonary scedosporiosis caused by Lomentospora prolificans in a patient who is immunocompetent: A rare case report

International Journal of Infectious Diseases, 2023
: Infections with Scedosporium and Lomentospora species are usually found in patients who are immunodeficient, particularly in the transplant population. However, they are relatively rare in patients who are immunocompetent, which is especially useful in
Xiqian Xing, Qian Liu, Wenli Yuan, Chenshao Zhu, Jiao Yang   +4 more
doaj   +1 more source

Voriconazole‐Associated Periostitis: New Insights into Pathophysiology and Management

JBMR Plus, Volume 6, Issue 2, February 2022., 2022
ABSTRACT Voriconazole‐associated periostitis (VAP) is an underrecognized and unpredictable side effect of long‐term voriconazole therapy. We report two cases of VAP occurring in the post‐transplant setting: a 68‐year‐old lung transplant recipient who required ongoing voriconazole therapy, in whom urinary alkalinization was used to promote fluoride ...
Michael J Bennett, Matthew I Balcerek, Edward AD Lewis, Roland LL Zhang, Caroline Bachmeier, Siok Tey, Steven Faux, Laila Girgis, Jerry R Greenfield, Syndia Lazarus   +9 more
wiley   +1 more source

Crossover between the control of fungal pathogens in medicine and the wider environment, and the threat of antifungal resistance

Plant Pathology, Volume 71, Issue 1, Page 131-149, January 2022., 2022
The origin and emergence of resistance to antifungal compounds are evaluated and potential “hot spots” identified for major life‐theatening fungal human pathogens in medical and environmental settings. Abstract Fungal propagules existing in the natural environment can easily be transmitted to the human body, mostly by inhalation of contaminated air or ...
Ulrich Gisi
wiley   +1 more source

Dot Immunobinding Assay for the Rapid Serodetection of Scedosporium/Lomentospora in Cystic Fibrosis Patients [PDF]

, 2023
Scedosporium; Cystic fibrosis; Serological detectionScedosporium; Fibrosi quística; Detecció serològicaScedosporium; Fibrosis quística; Detección serológicaThe detection of Scedosporium/Lomentospora is still based on non-standardized low-sensitivity ...
Antoran, Aitziber, Aparicio-Fernandez, Leire, Areitio, Maialen, Fernandez, Roberto, Martin Gomez, M Teresa, Martin Souto, Leire   +5 more
core   +5 more sources

Acupuncture‐Associated Mycobacterium massiliense and Scedosporium Infections Superimposed by Tetanus

Case Reports in Infectious Diseases, Volume 2022, Issue 1, 2022., 2022
Background. Tetanus has rarely been reported in Thailand since 1982 due to 100% tetanus vaccination coverage during the neonatal period of life. However, the reemergence of tetanus has been observed in our country during the past decade, mainly due to the increasing number of migrants traveling from neighboring countries in search of work.
Thaninee Prasoppokakorn, Mohd Adnan
wiley   +1 more source

Lomentospora prolificans vertebral osteomyelitis with spinal epidural abscess in an immunocompetent woman: Case report and literature review

Medical Mycology Case Reports, 2018
Lomentospora prolificans is a rare cause of vertebral osteomyelitis. We report a case of L. prolificans thoracic vertebral osteomyelitis with spinal epidural abscess in a patient without apparent immunodeficiency. Clinical manifestations and radiographic
Walaiporn Wangchinda, Piriyaporn Chongtrakool, Jantima Tanboon, Anupop Jitmuang   +3 more
doaj   +1 more source

Masquerading Yeast: A Case Report of <i>Lomentospora prolificans</i> Fungemia With a Diagnostic Twist. [PDF]

Open Forum Infect Dis
Abstract Lomentospora prolificans is an environmental mold that is increasingly recognized as an opportunistic pathogen, particularly in immunocompromised hosts. Here we present a case of disseminated Lomentospora in a patient with refractory acute myeloid leukemia.
Fenlon LA, Swaminathan N.
europepmc   +3 more sources

Bis(N‐picolinamido)cobalt(II) Complexes Display Antifungal Activity toward Candida albicans and Aspergillus fumigatus

ChemMedChem, Volume 16, Issue 20, Page 3210-3221, October 15, 2021., 2021
Bis(N‐picolinamide)cobalt(II) complexes containing trans isothiocyanate ligands are reported to have significantly enhanced activity toward fungal species, when compared the cis complexes. They display >80 % growth inhibition of fungal strains and no reported toxicity toward bacterial species or mammalian cells.
Laura H. D. Ghandhi, Stefan Bidula, Christopher M. Pask, Rianne M. Lord, Patrick C. McGowan   +4 more
wiley   +1 more source