Identification of Filamentous Fungi: An Evaluation of Three MALDI‐TOF Mass Spectrometry Systems
ABSTRACT Background Identification of filamentous fungi still poses a major challenge to laboratories. Matrix assisted laser desorption/ionisation time of flight mass spectrometry (MALDI‐TOF MS) is a promising tool, since it offers low‐cost and fast results. Different MALDI‐TOF MS systems are available for routine laboratories.
Isabel Klugherz +6 more
wiley +1 more source
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley +2 more
wiley +1 more source
Clinical usefulness of triazole derivatives in the management of fungal infections [PDF]
El tratamiento de las infecciones producidas por hongos se limita al uso de un reducido número de moléculas. Si bien, la anfotericina B aún sigue siendo considerada como el antifúngico de referencia, para el tratamiento de estas infecciones, la toxicidad
Arechavala, Alicia +7 more
core
The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley +1 more source
ABSTRACT Background The airways of patients with cystic fibrosis (pwCF) harbour complex fungal and bacterial microbiota involved in pulmonary exacerbations (PEx) and requiring antimicrobial treatment. Descriptive studies analysing bacterial and fungal microbiota concomitantly are scarce, especially using both culture and high‐throughput‐sequencing (HTS)
Cécile Angebault +11 more
wiley +1 more source
Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum [PDF]
Scedosporium spp. are the second most prevalent filamentous fungi after Aspergillus spp. recovered from cystic fibrosis (CF) patients in various regions of the world.
Abdullah, Sarimah +23 more
core +3 more sources
N -Chlorotaurine Exhibits Fungicidal Activity against Therapy-Refractory Scedosporium Species and Lomentospora prolificans [PDF]
ABSTRACT N -Chlorotaurine (NCT), a well-tolerated endogenous long-lived oxidant that can be applied topically as an antiseptic, was tested on its fungicidal activity against Scedosporium and Lomentospora , opportunistic fungi that cause severe infections with limited ...
Michaela, Lackner +6 more
openaire +2 more sources
Dihydroorotate dehydrogenase inhibitor F901318 has potent in vitro activity against Scedosporium species and Lomentospora prolificans [PDF]
Scedosporium species and Lomentospora prolificans are increasing causes of invasive infections in immunocompromised hosts and many isolates are resistant to available antifungals. Our objective was to assess the in vitro potency of F901318, a member of the orotomide class of antifungals, against Scedosporium species and L.
Nathan P, Wiederhold +2 more
openaire +2 more sources
Papel de peptidoramnomananas nas interações polimicrobianas entre espécies de Scedosporium/Lomentospora e bactérias de relevância clínica na fibrose cística [PDF]
A fibrose cística é uma doença genética causada pela mutação no gene que codifica a proteína CFTR. Essa desordem gera um desequilíbrio de eletrólitos e água que leva a formação de um muco altamente viscoso nas vias aéreas, que não é facilmente eliminado,
Oliveira, Evely Bertulino de
core
Isolasi Jamur Kapang dari Tanah [PDF]
Tanah merupakan habitat berbagai mikroorganisme termasuk jamur. Jamur yang hidup di tanah termasuk jamur patogen untuk manusia. Antara lain golongan dermatofita, Aspergillus, dan Mucorales.
Hani, Safira +4 more
core +2 more sources

