Results 171 to 180 of about 189,217 (189)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran   +5 more
wiley   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi   +3 more
wiley   +1 more source

Sustaining the teaching profession: Innovating the ‘golden thread’ in university‐led teacher education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper examines the implications of England's ‘golden thread’ policy framework for teacher education, which describes a state‐mandated, linear model of professional learning from initial teacher training and education through to continuing professional development.
Amanda Nuttall   +3 more
wiley   +1 more source

Teacher‐makers and teacher‐breakers: (Re)defining how status and safety influence trajectories into and away from teaching

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper uses empirical data from a longitudinal qualitative study conducted with aspirant teachers in England to propose (re)definitions of the concepts of ‘status’ and ‘safety’ as a framework with which to understand and improve teacher recruitment.
Emily MacLeod
wiley   +1 more source

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