Results 51 to 60 of about 519,655 (258)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Long Covid - never ending story

Sri Lanka Journal of Medicine, 2021
No abstract ...
D. Madegedara
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Association between olfactory dysfunction and mood disturbances with objective and subjective cognitive deficits in long-COVID

Frontiers in Psychology, 2023
Background and purposeThe coronavirus disease 2019 (COVID-19) has been associated with olfactory dysfunction. The persistent symptoms of anosmia or hyposmia were associated in previous studies with the development of memory impairment and mood ...
Tania Llana, Tania Llana, Tania Llana, Tania Llana, Marta Mendez, Marta Mendez, Marta Mendez, Sara Garces-Arilla, Sara Garces-Arilla, Vanesa Hidalgo, Vanesa Hidalgo, Magdalena Mendez-Lopez, Magdalena Mendez-Lopez, M.-Carmen Juan   +13 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Co-design of a voice-based app to monitor long COVID symptoms with its end-users: A mixed-method study

Digital Health
Background People living with Long COVID (PWLC), which is still a poorly understood disease, often face major issues accessing proper care and frequently feel abandoned by the healthcare system.
Aurélie Fischer, Gloria Aguayo, India Pinker, Pauline Oustric, Tom Lachaise, Paul Wilmes, Jérôme Larché, Charles Benoy, Guy Fagherazzi   +8 more
doaj   +1 more source

What Are People Asking About COVID-19? A Question Classification Dataset

, 2020
We present COVID-Q, a set of 1,690 questions about COVID-19 from 13 sources, which we annotate into 15 question categories and 207 question clusters. The most common questions in our dataset asked about transmission, prevention, and societal effects of ...
Huang, Chengyu, Vosoughi, Soroush, Wei, Jason, Wei, Jerry   +3 more
core  

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Four Years in, What Are the Research Priorities for Long COVID? A Research Priority‐Setting Partnership Between People With Lived Experience, Carers, Clinicians and Researchers

Health Expectations
Introduction Long COVID is a life‐limiting condition that affects 65 million people worldwide. It devastates lives with uncertain illness trajectories, and yet, there are many research uncertainties as there is a lack of understanding of its causes ...
Aileen Grant, Emma Stage, David Blane, Helen Goss, Jane Ormerod, Stuart McIver, Edward Duncan, Gail Patel, Abi Campbell, Paul Manson, Ganesh Subramanian, Kay Cooper   +11 more
doaj   +1 more source

Pediatric Long COVID [PDF]

The emergence of long COVID, a condition characterized by persistent symptoms lasting beyond the acute phase of COVID-19 infection, has raised concerns about its impact on pediatric populations.
Hümmert, Veith, Schwarz, Stefan
core   +2 more sources