Results 41 to 50 of about 12,771,625 (248)

An Early Forecast of Long‐Period Ground Motions of Large Earthquakes Based on Deep Learning

open access: yesGeophysical Research Letters, 2023
Long‐period (LP; approximately 2–10 s) ground motions generated by large earthquakes are amplified in large basins and threaten high‐rise buildings in modern cities.
Takashi Furumura, Yusuke Oishi
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Primary visual cortex activity along the apparent-motion trace reflects illusory perception [PDF]

open access: yes, 2005
The illusion of apparent motion can be induced when visual stimuli are successively presented at different locations. It has been shown in previous studies that motion-sensitive regions in extrastriate cortex are relevant for the processing of apparent ...
Kriegeskorte, Nikolaus   +19 more
core   +2 more sources

A Comparative Centrifuge Test Study on the Influence of Overlying Seawater on Seismic Response Spectrum

open access: yesJournal of Marine Science and Engineering, 2023
In this study, dynamic centrifugal model tests for two homogeneous saturated soft clay sites are designed to analyze the influence of overlying sea water on ground motion.
Juan Liu   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Simulation of long-period ground motion near a large earthquake [PDF]

open access: yes, 1997
We estimated the possible range of long-period ground motion for sites located on a soft sedimentary basin in the immediate vicinity of a large ...
Minoru Takeo   +3 more
core  

Ground motion prediction equations based on shallow crustal earthquakes in Georgia and the surrounding Caucasus

open access: yesEarthquake Science, 2022
Strong ground motions caused by earthquakes with magnitudes ranging from 3.5 to 6.9 and hypocentral distances of up to 300 km were recorded by local broadband stations and three-component accelerograms within Georgia’s enhanced digital seismic network ...
Nato Jorjiashvili   +4 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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