Results 131 to 140 of about 7,939,670 (409)

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Ontario case costing: A catalyst for transforming Ontario’s health system into a value-based model

open access: yesInternational Journal of Population Data Science, 2018
Introduction Case costing is the only source of integrated financial, clinical, and utilization data at the patient level in Ontario. This accounting tool improves funding and performance management processes and tracks health care service costs for ...
Jianing Zheng
doaj   +1 more source

Projections of the general and elderly population of Texas, 1970-2000 : by senatorial districts [PDF]

open access: yes, 1979
The data presented in this publication were developed by the Joint Committee on Long-Term Care Alternatives in its study of the elderly population of Texas and the effectiveness of various services in meeting the needs of that population.
Texas Joint Committee on Long-Term Care Alternatives
core   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Analysis of outcomes from a geriatrician-led evidence-based falls prevention clinic: a retrospective study from Qatar

open access: yesThe Aging Male
Background Falls are an important health concern among older persons. This study attempted to evaluate the characteristics and risk factors of falls in older persons attending a geriatric falls clinic in Qatar, with a particular emphasis on the impact of
Hanadi Al Hamad, Brijesh Sathian
doaj   +1 more source

Transition to adult care in young people with neuromuscular disease on non-invasive ventilation

open access: yesItalian Journal of Pediatrics, 2019
Background Long-term mechanical ventilation (LTV) with non-invasive ventilation (NIV) prolongs survival in patients with Neuromuscular Diseases (NMDs).
Alessandro Onofri   +7 more
doaj   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

The Lithuanian Long-term Care System [PDF]

open access: yes, 2010
The remarkable growth of older population has moved long-term care to the front ranks of the social policy agenda in the European Union. This paper addresses the issue of the longterm care in Lithuania, its philosophy, the legal and funding regularities,
Marcinkowska, Izabela
core  

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

open access: yesMolecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns   +4 more
wiley   +1 more source

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