Results 121 to 130 of about 3,359,811 (316)

Apnea of prematurity induces short and long-term development-related transcriptional changes in the murine cerebellum. [PDF]

open access: yesCurr Res Neurobiol, 2023
Rodriguez-Duboc A   +5 more
europepmc   +1 more source

Panorama of Aging and Long-Term Care: Summary Argentina

open access: yes, 2020
Argentina case study summary website "Panorama of Aging and Long-term Care"
Inter-American Development Bank
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Prevalence and factors associated with postpartum depressive symptoms among mothers who gave birth within the past 12 months in Ghana: mixed-method study

open access: yesBJPsych Open
Background Postpartum depressive symptoms (PPDS) are mental health concerns, characterised by sadness, anxiety and suicidal ideation. Aims We aimed to estimate the prevalence of PPDS, identify its associated factors and explore the lived experiences ...
Leticia Tornyevah   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

What If Leisure Time Activities Were a Solution for Athletes' Long-Term Development and Health? [PDF]

open access: yesFront Psychol, 2022
Vacher P   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

BASIS OF STRUCTURAL-INVESTMENT POLICY IN MODERN CONDITIONS OF RUSSIAN ECONOMY

open access: yesФинансы: теория и практика, 2017
The article describes the principles of structural and investment policy, which should become one of the elements of a long-term economic strategy aimed at eliminating development disparities that have emerged in the last two decades and can not be ...
V. V. Ivanter   +3 more
doaj  

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