Results 181 to 190 of about 3,359,811 (316)

Microbial physiology conserves phosphorus across long-term ecosystem development

Long-term terrestrial ecosystem development is characterized by declining soil phosphorus (P) and a corresponding increase in biological P limitation.
Matsumura, S, Manzoni, S, Butler, OM, Liang, G, Warren, CR   +4 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Exploring the role of plant-animal interactions in the long-term development of heritage landscapes in Europe. [PDF]

Philos Trans R Soc Lond B Biol Sci
Dal Corso M, Salavert A, Marinova E, Gillis RE.   +3 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Long-Term Development of Training Characteristics and Physiological Determinants in World-Leading and Medal-Winning Female Cross-Country Skiers: A Three Decade Comparative Analysis. [PDF]

Sports Med Open
Staff H, Solli GS, Welde B, Tønnessen E, Sandbakk Ø.   +4 more
europepmc   +1 more source

Preliminary evaluations of 3-dimensional human skin models for their ability to facilitate in vitro the long-term development of the debilitating obligatory human parasite Onchocerca volvulus. [PDF]

PLoS Negl Trop Dis, 2020
Malkmus C, Jawahar S, Tricoche N, Lustigman S, Hansmann J.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Causal analysis of traditional and environmental risk factors for long-term development of type 2 diabetes using a conditional survival Bayesian network: evidence from the Korean Genome and Epidemiology Study. [PDF]

BMC Public Health
Choi JY, Oh MS.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Chemotherapy-induced cognitive impairment and its long-term development in patients with breast cancer: results from the observational CICARO study. [PDF]

Oncologist
Kerkmann A, Schinke C, Dordevic A, Kern J, Bangemann N, Finck J, Blohmer JU, Ruprecht K, Göpfert JC, Otto C, Materne B, Endres M, Boehmerle W, Huehnchen P.   +13 more
europepmc   +1 more source