Results 51 to 60 of about 2,308,826 (317)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Short-term plasticity as cause-effect hypothesis testing in distal reward learning [PDF]

open access: yes, 2014
Asynchrony, overlaps and delays in sensory-motor signals introduce ambiguity as to which stimuli, actions, and rewards are causally related. Only the repetition of reward episodes helps distinguish true cause-effect relationships from coincidental ...
Soltoggio, Andrea
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Disruption of Memory Consolidation of Duration Introduces Noise While Lengthening the Long-Term Memory Representation of Time in Humans

open access: yesFrontiers in Psychology, 2019
This study examined the effect of an interference task on the consolidation of duration in long-term memory. In a temporal generalization task, the participants performed a learning phase with a reference duration that either was, or was not, followed 30
Joffrey Derouet   +2 more
doaj   +1 more source

Lived Experiences of Everyday Memory in Adults with Dyslexia: A Thematic Analysis

open access: yesBehavioral Sciences, 2023
Dyslexia-related difficulties with memory are well documented under laboratory conditions and via self-report questionnaires. However, the voice of the individual with dyslexia regarding the lived experience of memory across different memory systems and ...
James Hugo Smith-Spark, Elisa G. Lewis
doaj   +1 more source

Does New Zealand visitors follow the Joseph Effect? Some empirical evidence [PDF]

open access: yes, 2011
The report departs from conventional time series analysis and investigates the existence of long memory (LRD) in the stream of daily visitors, arriving from various sources to New Zealand from 1997 to 2010, using selected estimators of the Hurst-exponent.
Foo, Dani
core   +1 more source

Orienting Attention Based on Long-Term Memory Improves Perceptual Discriminations [PDF]

open access: yes, 2009
The role of attentional orienting in daily life is to selectively deploy both behavioural and neural resources towards events, based on continually changing task goals and expectations, in order to optimize performance.
Anling Rao   +3 more
core   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Short‐term wind power prediction based on combined long short‐term memory

open access: yesIET Generation, Transmission & Distribution
Wind power is an exceptionally clean source of energy; its rational utilization can fundamentally alleviate the energy, environment, and development problems, especially under the goals of ‘carbon peak’ and ‘carbon neutrality’. A combined short‐term wind
Yuyang Zhao   +4 more
doaj   +1 more source

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