Results 91 to 100 of about 1,220,900 (264)

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Growth and Performance: Business Model Innovation in Family Firms

Businesses
A business model, defined as the underlying logic of a company, is not permanent over time. Instead, companies need to introduce innovations in the business model to be competitive in the market.
Angel-Luis Meroño-Cerdan, Francisco-Jose Molina-Castillo, Carolina Lopez-Nicolas, Jesus Ruiz-Nicolas   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Long‐Term Blood Pressure Variability and Physical Performance in Older Adults

The Journal of Clinical Hypertension
High variability in long‐term blood pressure (BPV) independently predicts cardiovascular disease and cognitive decline. Increased BPV and declining physical performance may share mechanistic pathways. However, associations of BPV with gait speed and grip
Kerry M. Sheets, Katherine L. Webb, Robyn L. Woods, Suzanne G. Orchard, Lawrence Beilin, Michelle A. Fravel, Christopher M. Reid, Kevan R. Polkinghorne, Rory Wolfe, Zhen Zhou, Joanne Ryan, Anne M. Murray, Michael E. Ernst   +12 more
doaj   +1 more source

The Long-Term Performance of a High-Density Polyethylene Geomembrane with Non-Parametric Statistic Analysis and Its Contribution to the Sustainable Development Goals

Applied Sciences
The tailings from gold beneficiation can cause various negative impacts, necessitating measures to prevent their transport and environmental contamination.
Beatriz M. C. Urashima, Renato Santos, Lucas D. Ferreira, Toru Inui, Denise C. Urashima, Anderson R. Duarte   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

LONG TERM PERFORMANCE OF EXISTING PORTLAND CEMENT CONCRETE PAVEMENT SECTIONS – CASE STUDY

Dyna, 2014
La presente investigación presenta el desempeño de diecisiete pavimentos rígidos hechos de Concreto con Cemento Portland (PCC) localizados en el Estado de Ohio, USA. La metodología de ensayos con el Deflectómetro de Impacto (FWD) se usó en un total de 58
SHAD M. SARGAND, CARLOS A. VEGA-POSADA, LUIS G. ARBOLEDA-MONSALVE   +2 more
doaj