Results 101 to 110 of about 3,231,981 (288)
In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow +10 morewiley +1 more sourceFirst Very Long Baseline Interferometry Detections at 870 μm
The Astronomical JournalThe first very long baseline interferometry (VLBI) detections at 870 μ m wavelength (345 GHz frequency) are reported, achieving the highest diffraction-limited angular resolution yet obtained from the surface of the Earth and the highest-frequency ...Alexander W. Raymond, Sheperd S. Doeleman, Keiichi Asada, Lindy Blackburn, Geoffrey C. Bower, Michael Bremer, Dominique Broguiere, Ming-Tang Chen, Geoffrey B. Crew, Sven Dornbusch, Vincent L. Fish, Roberto García, Olivier Gentaz, Ciriaco Goddi, Chih-Chiang Han, Michael H. Hecht, Yau-De Huang, Michael Janssen, Garrett K. Keating, Jun Yi Koay, Thomas P. Krichbaum, Wen-Ping Lo, Satoki Matsushita, Lynn D. Matthews, James M. Moran, Timothy J. Norton, Nimesh Patel, Dominic W. Pesce, Venkatessh Ramakrishnan, Helge Rottmann, Alan L. Roy, Salvador Sánchez, Remo P. J. Tilanus, Michael Titus, Pablo Torne, Jan Wagner, Jonathan Weintroub, Maciek Wielgus, André Young, Kazunori Akiyama, Ezequiel Albentosa-Ruíz, Antxon Alberdi, Walter Alef, Juan Carlos Algaba, Richard Anantua, Rebecca Azulay, Uwe Bach, Anne-Kathrin Baczko, David Ball, Mislav Balokovic, Bidisha Bandyopadhyay, John Barrett, Michi Bauböck, Bradford A. Benson, Dan Bintley, Raymond Blundell, Katherine L. Bouman, Hope Boyce, Roger Brissenden, Silke Britzen, Avery E. Broderick, Thomas Bronzwaer, Sandra Bustamante, John E. Carlstrom, Andrew Chael, Chi-kwan Chan, Dominic O. Chang, Koushik Chatterjee, Shami Chatterjee, Yongjun Chen, Xiaopeng Cheng, Ilje Cho, Pierre Christian, Nicholas S. Conroy, John E. Conway, Thomas M. Crawford, Alejandro Cruz-Osorio, Yuzhu Cui, Rohan Dahale, Jordy Davelaar, Mariafelicia De Laurentis, Roger Deane, Jessica Dempsey, Gregory Desvignes, Jason Dexter, Vedant Dhruv, Indu K. Dihingia, Sergio A. Dzib, Ralph P. Eatough, Razieh Emami, Heino Falcke, Joseph Farah, Edward Fomalont, Anne-Laure Fontana, H. Alyson Ford, Marianna Foschi, Raquel Fraga-Encinas, William T. Freeman, Per Friberg, Christian M. Fromm, Antonio Fuentes, Peter Galison, Charles F. Gammie, Boris Georgiev, Roman Gold, Arturo I. Gómez-Ruiz, José L. Gómez, Minfeng Gu, Mark Gurwell, Kazuhiro Hada, Daryl Haggard, Ronald Hesper, Dirk Heumann, Luis C. Ho, Paul Ho, Mareki Honma, Chih-Wei L. Huang, Lei Huang, David H. Hughes, Shiro Ikeda, C. M. Violette Impellizzeri, Makoto Inoue, Sara Issaoun, David J. James, Buell T. Jannuzi, Britton Jeter, Wu Jiang, Alejandra Jiménez-Rosales, Michael D. Johnson, Svetlana Jorstad, Adam C. Jones, Abhishek V. Joshi, Taehyun Jung, Ramesh Karuppusamy, Tomohisa Kawashima, Mark Kettenis, Dong-Jin Kim, Jae-Young Kim, Jongsoo Kim, Junhan Kim, Motoki Kino, Prashant Kocherlakota, Yutaro Kofuji, Patrick M. Koch, Shoko Koyama, Carsten Kramer, Joana A. Kramer, Michael Kramer, Derek Kubo, Cheng-Yu Kuo, Noemi La Bella, Sang-Sung Lee, Aviad Levis, Zhiyuan Li, Rocco Lico, Greg Lindahl, Michael Lindqvist, Mikhail Lisakov, Jun Liu, Kuo Liu, Elisabetta Liuzzo, Andrei P. Lobanov, Laurent Loinard, Colin J. Lonsdale, Amy E. Lowitz, Ru-Sen Lu, Nicholas R. MacDonald, Sylvain Mahieu, Doris Maier, Jirong Mao, Nicola Marchili, Sera Markoff, Daniel P. Marrone, Alan P. Marscher, Iván Martí-Vidal, Lia Medeiros, Karl M. Menten, Izumi Mizuno, Yosuke Mizuno, Joshua Montgomery, Kotaro Moriyama, Monika Moscibrodzka, Wanga Mulaudzi, Cornelia Müller, Hendrik Müller, Alejandro Mus, Gibwa Musoke, Ioannis Myserlis, Hiroshi Nagai, Neil M. Nagar, Masanori Nakamura, Gopal Narayanan, Iniyan Natarajan, Antonios Nathanail, Santiago Navarro Fuentes, Joey Neilsen, Chunchong Ni, Michael A. Nowak, Junghwan Oh, Hiroki Okino, Héctor Raúl Olivares Sánchez, Tomoaki Oyama, Feryal Özel, Daniel C. M. Palumbo, Georgios Filippos Paraschos, Jongho Park, Harriet Parsons, Ue-Li Pen, Vincent Piétu, Aleksandar PopStefanija, Oliver Porth, Ben Prather, Giacomo Principe, Dimitrios Psaltis, Hung-Yi Pu, Philippe A. Raffin, Ramprasad Rao, Mark G. Rawlings, Angelo Ricarte, Bart Ripperda, Freek Roelofs, Cristina Romero-Cañizales, Eduardo Ros, Arash Roshanineshat, Ignacio Ruiz, Chet Ruszczyk, Kazi L. J. Rygl, David Sánchez-Argüelles, Miguel Sánchez-Portal, Mahito Sasada, Kaushik Satapathy, Tuomas Savolainen, F. Peter Schloerb, Jonathan Schonfeld, Karl-Friedrich Schuster, Lijing Shao, Zhiqiang Shen, Des Small, Bong Won Sohn, Jason SooHoo, León David Sosapanta Salas, Kamal Souccar, Ranjani Srinivasan, Joshua S. Stanway, He Sun, Fumie Tazaki, Alexandra J. Tetarenko, Paul Tiede, Kenji Toma, Teresa Toscano, Efthalia Traianou, Tyler Trent, Sascha Trippe, Matthew Turk, Ilse van Bemmel, Huib Jan van Langevelde, Daniel R. van Rossum, Jesse Vos, Derek Ward-Thompson, John Wardle, Jasmin E. Washington, Robert Wharton, Kaj Wiik, Gunther Witzel, Michael F. Wondrak, George N. Wong, Qingwen Wu, Nitika Yadlapalli, Paul Yamaguchi, Aristomenis Yfantis, Doosoo Yoon, Ziri Younsi, Wei Yu, Feng Yuan, Ye-Fei Yuan, J. Anton Zensus, Shuo Zhang, Guang-Yao Zhao, Shan-Shan Zhao +278 moredoaj +1 more sourceEffect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees +6 morewiley +1 more sourceTerrestrial very-long-baseline atom interferometry: Workshop summary [PDF]
AVS Quantum ScienceThis document presents a summary of the 2023 Terrestrial Very-Long-Baseline Atom Interferometry Workshop hosted by CERN. The workshop brought together experts from around the world to discuss the exciting developments in large-scale atom interferometer (AI) prototypes and their potential for detecting ultralight dark matter and gravitational waves. The Abend, Sven, Allard, Baptiste, Alonso, Ivan, Antoniadis, John, Araujo, Henrique, Arduini, Gianluigi, Arnold, Aidan S., Asano, Tobias, Augst, Nadja, Badurina, Leonardo, Balaz, Antun, Banks, Hannah, Barone, Michele, Barsanti, Michele, Bassi, Angelo, Battelier, Baptiste, Baynham, Charles F.A., Beaufils, Quentin, Belic, Aleksandar, Beniwal, Ankit, Bernabeu, Jose, Bertinelli, Francesco, Bertoldi, Andrea, Biswas, Ikbal Ahamed, Blas, Diego, Boegel, Patrick, Bogojevic, Aleksandar, Boehm, Jonas, Boehringer, Samuel, Bongs, Kai, Bouyer, Philippe, Brand, Christian, Brimis, Apostolos, Buchmueller, Oliver, Cacciapuoti, Luigi, Calatroni, Sergio, Canuel, Benjamin, Caprini, Chiara, Caramete, Ana, Caramete, Laurentiu, Carlesso, Matteo, Carlton, John, Casariego, Mateo, Charmandaris, Vassilis, Chen, Yu-Ao, Chiofalo, Maria Luisa, Cimbri, Alessia, Coleman, Jonathon, Constantin, Florin Lucian, Contaldi, Carlo R., Cui, Yanou, Ros, Elisa Da, Davies, Gavin, Rosendo, Esther del Pino, Deppner, Christian, Derevianko, Andrei, de Rham, Claudia, De Roeck, Albert, Derr, Daniel, Di Pumpo, Fabio, Djordjevic, Goran S., Doebrich, Babette, Domokos, Peter, Dornan, Peter, Doser, Michael, Drougakis, Giannis, Dunningham, Jacob, Duspayev, Alisher, Easo, Sajan, Eby, Joshua, Efremov, Maxim, Ekelof, Tord, Elertas, Gedminas, Ellis, John, Evans, David, Fadeev, Pavel, Fani, Mattia, Fassi, Farida, Fattori, Marco, Fayet, Pierre, Felea, Daniel, Feng, Jie, Friedrich, Alexander, Fuchs, Elina, Gaaloul, Naceur, Gao, Dongfeng, Gardner, Susan, Garraway, Barry, Gauguet, Alexandre, Gerlach, Sandra, Gersemann, Matthias, Gibson, Valerie, Giese, Enno, Giudice, Gian F., Glasbrenner, Eric P., Guendogan, Mustafa, Haehnelt, Martin, Hakulinen, Timo, Hammerer, Klemens, Hanimeli, Ekim T., Harte, Tiffany, Hawkins, Leonie, Hees, Aurelien, Heise, Jaret, Henderson, Victoria A., Herrmann, Sven, Hird, Thomas M., Hogan, Jason M., Holst, Bodil, Holynski, Michael, Hussain, Kamran, Janson, Gregor, Jeglic, Peter, Jelezko, Fedor, Kagan, Michael, Kalliokoski, Matti, Kasevich, Mark, Kehagias, Alex, Kilian, Eva, Koley, Soumen, Konrad, Bernd, Kopp, Joachim, Kornakov, Georgy, Kovachy, Tim, Krutzik, Markus, Kumar, Mukesh, Kumar, Pradeep, Laemmerzahl, Claus, Landsberg, Greg, Langlois, Mehdi, Lanigan, Bryony, Lellouch, Samuel, Leone, Bruno, Poncin-Lafitte, Christophe Le, Lewicki, Marek, Leykauf, Bastian, Lezeik, Ali, Lombriser, Lucas, Luis Lopez-Gonzalez, J., Lopez Asamar, Elias, Monjaraz, Cristian Lopez, Luciano, Giuseppe Gaetano, Mahmoud, M.A., Maleknejad, Azadeh, Krutzik, Markus, Marteau, Jacques, Massonnet, Didier, Mazumdar, Anupam, McCabe, Christopher, Meister, Matthias, Menu, Jonathan, Messineo, Giuseppe, Micalizio, Salvatore, Millington, Peter, Milosevic, Milan, Mitchell, Jeremiah, Montero, Mario, Morley, Gavin W., Mueller, Juergen, Mustecaploglu, Ozgur E., Ni, Wei-Tou, Noller, Johannes, Odzak, Senad, Oi, Daniel K.L., Omar, Yasser, Pahl, Julia, Paling, Sean, Pandey, Saurabh, Pappas, George, Pareek, Vinay, Pasatembou, Elizabeth, Pelucchi, Emanuele, dos Santos, Franck Pereira, Piest, Baptist, Pikovski, Igor, Pilaftsis, Apostolos, Plunkett, Robert, Poggiani, Rosa, Prevedelli, Marco, Puputti, Julia, Veettil, Vishnupriya Puthiya, Quenby, John, Rafelski, Johann, Rajendran, Surjeet, Rasel, Ernst M., Sfar, Haifa Rejeb, Reynaud, Serge, Richaud, Andrea, Rodzinka, Tangui, Roura, Albert, Rudolph, Jan, Sabulsky, Dylan O., Safronova, Marianna S., Santamaria, Luigi, Schilling, Manuel, Schkolnik, Vladimir, Schleich, Wolfgang P., Schlippert, Dennis, Schneider, Ulrich, Schreck, Florian, Schwersenz, Nico, Semakin, Aleksei, Sergijenko, Olga, Shao, Lijing, Singh, Rajeev, Sopuerta, Carlos F., Stergioulas, Nikolaos, Throssell, Henry, Tino, Guglielmo M., Tinsley, Jonathan N., Torres-Orjuela, Alejandro, Treutlein, Philipp, Trombettoni, Andrea, Tsai, Yu-Dai, Vaskonen, Ville, Werner, Michael, Windpassinger, Patrick, Wolf, Peter, Yahia, Mohamed E., Cruzeiro, Emmanuel Zambrini, Zarei, Moslem, Zhan, Mingsheng +221 moreopenaire +13 more sourcesExploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair +17 morewiley +1 more source
