Results 131 to 140 of about 3,231,981 (288)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Long-Baseline Atom Interferometry

Submission to the 2026 update of the European Strategy for Particle Physics on behalf of the TVLBAI Proto-Collaboration: V2: Minor corrections to author ...
Balaz, Antun, Blas, Diego, Buchmueller, Oliver, Calatroni, Sergio, Caramete, Laurentiu-Ioan, Cerdeno, David, Chiofalo, Maria Luisa, Di Pumpo, Fabio, Djordjevic, Goran, Ellis, John, Fayet, Pierre, Foot, Chris, Gaaloul, Naceur, Gardner, Susan, Garraway, Barry M, Gauguet, Alexandre, Giese, Enno, Hogan, Jason M., Hosten, Onur, Kehagias, Alex, Kilian, Eva, Kovachy, Tim, Lacasta, Carlos, Lewicki, Marek, Asamar, Elias Lopez, Lopez-Gonzalez, J. Luis, Lundblad, Nathan, Maggiore, Michele, McCabe, Christopher, McFerran, John, Mileti, Gaetano, Millington, Peter, Morley, Gavin W., Odzak, Senad, Overstreet, Chris, Pawlowski, Krzysztof, Pelucchi, Emanuele, Rafelski, Johann, Roura, Albert, Safronova, Marianna S., Schreck, Florian, Sergijenko, Olga, Singh, Yeshpal, Soares-Santos, Marcelle, Stergioulas, Nikolaos, Tino, Guglielmo M., Tinsley, J. N., Ulbricht, Hendrik, van der Grinten, Maurits, Vaskonen, Ville, von Klitzing, Wolf, Xuereb, Andre, Cruzeiro, Emmanuel Zambrini   +52 more
openaire   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Practical approach to extending baselines of telescopes using continuous-variable quantum information

New Journal of Physics
Interferometric telescopes are instrumental for the imaging of distant astronomical bodies, but optical loss heavily restricts how far telescopes in an array can be placed from one another, leading to a bottleneck in the resolution that can be achieved ...
Bran Purvis, Randy Lafler, R Nicholas Lanning   +2 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Supermassive Black Hole Spin Constraints from Polarimetry in an Equatorial Disk Model

The Astrophysical Journal Letters
The Event Horizon Telescope has released polarized images of the supermassive black holes Messier 87* (M87*) and Sagittarius A* accretion disks. As more images are produced, our understanding of the average polarized emission from near the event horizon ...
Daniel C. M. Palumbo
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Long Baseline Neutrinos [PDF]

Proceedings of 36th International Conference on High Energy Physics — PoS(ICHEP2012), 2013
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source