Results 81 to 90 of about 3,231,981 (288)

Criteria for optimal entanglement-assisted long baseline telescopy

open access: yesPhysical Review Research
Entanglement-assisted telescopy protocols have been proposed as a means to extend the baseline of optical interferometric telescopes. However, the optimal entangled resource and a clear optimality criterion have remained unclear.
Yujie Zhang, Thomas Jennewein
doaj   +1 more source

Long baseline vector determinations and intercomparisons [PDF]

open access: yes
The East Coast very long baseline interferometry (VLBI) group has performed about 60 experiments over the last 10 years in the process of developing and exploiting advanced VLBI techniques.
Knight, C. A.
core   +1 more source

Long Baseline Neutrino Oscillations: Parameter Degeneracies and JHF/NuMI Complementarity

open access: yes, 2003
A summary of the parameter degeneracy issue for long baseline neutrino oscillations is presented and how a sequence of measurements can be used to resolve all degeneracies.
Minakata, Hisakazu   +2 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Serial MultiView: An Efficient Approach to Mitigating Atmospheric Spatial-structure Errors for Very-long-baseline-interferometry Astrometry

open access: yesThe Astronomical Journal
Atmospheric propagation errors are a main constraint on the accuracy of very-long-baseline-interferometry astrometry. For relative astrometry, differential techniques can mitigate these errors, but their effectiveness diminishes with decreasing elevation
Jingdong Zhang   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A self-calibration approach for optical long baseline interferometry imaging

open access: yes, 2008
Current optical interferometers are affected by unknown turbulent phases on each telescope. In the field of radio-interferometry, the self-calibration technique is a powerful tool to process interferometric data with missing phase information. This paper
Benson   +20 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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