Results 31 to 40 of about 11,411,505 (259)
A Randomized Placebo-Controlled Trial of Sarilumab in Hospitalized Patients with Covid-19
, 2021 BACKGROUND: Sarilumab (anti-interleukin-6 receptor-α monoclonal antibody) may attenuate the inflammatory response in Covid-19. METHODS: We performed an adaptive, phase 2/3, randomized, double-blind, placebo-controlled trial of intravenous sarilumab 200 ...
DiCioccio, A. Thomas +39 more
core +1 more source
Who Is the Intermediate Host of RNA Viruses? A Study Focusing on SARS-CoV-2 and Poliovirus
MicroorganismsThe COVID-19 pandemic has sparked a surge in research on microbiology and virology, shedding light on overlooked aspects such as the infection of bacteria by RNA virions in the animal microbiome.
Carlo Brogna +9 more
doaj +1 more source
Reviews in Cardiovascular Medicine, 2023 Long COVID or post-acute Coronavirus disease 2019 (COVID-19), a malady defined by the persistence of COVID-19 symptoms for weeks or even months, is expected to affect the lives of millions of individuals worldwide significantly.
Nuraini Yasmin Kusumawardhani +9 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
COVID-19: Long-Term Effects of COVID-19 [PDF]
, 2021 Hovedbudskap: Denne hurtigoppsummeringen er en første oversikt om langtidseffekter av covid-19 (> 28 dager). Den 26. januar utførte vi et systematisk litteratursøk etter studier med mer enn 100 deltakere. Én forsker screenet søkeresultatene. To forskere
Gravningen, Kirsten Midttun +3 more
core +1 more source
Challenges in control of COVID-19: short doubling time and long delay to effect of interventions. [PDF]
, 2021 Early assessments of the growth rate of COVID-19 were subject to significant uncertainty, as expected with limited data and difficulties in case ascertainment, but as cases were recorded in multiple countries, more robust inferences could be made.
House, Thomas A +17 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Etoposide as Salvage Therapy for Cytokine Storm due to COVID-19
, 2020 Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality because of a lack of effective therapies. Therapeutic strategies under investigation target the overactive cytokine response with anti-cytokine or immunomodulators ...
Bromberg, Michael +10 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Pulmonary TherapyIntroduction Most hospitalized patients required invasive or non-invasive ventilation and High Flow Nasal Cannula (HFNC). Therefore, this study was conducted to describe the characteristics of patients with severe Coronavirus Disease—2019 (COVID-19 ...
Sy Duong-Quy +32 more
doaj +1 more source