Results 61 to 70 of about 8,205,191 (295)

Four Years in, What Are the Research Priorities for Long COVID? A Research Priority‐Setting Partnership Between People With Lived Experience, Carers, Clinicians and Researchers

Health Expectations
Introduction Long COVID is a life‐limiting condition that affects 65 million people worldwide. It devastates lives with uncertain illness trajectories, and yet, there are many research uncertainties as there is a lack of understanding of its causes ...
Aileen Grant, Emma Stage, David Blane, Helen Goss, Jane Ormerod, Stuart McIver, Edward Duncan, Gail Patel, Abi Campbell, Paul Manson, Ganesh Subramanian, Kay Cooper   +11 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Community Engagement in Long Covid Research: Process, Evaluation and Recommendations From the Long COVID and Episodic Disability Study

Health Expectations
Introduction Long Covid and other infection‐associated chronic condition communities have been integral in advocating for patient engagement in all stages of research, from design and conduct, and implementation, through to interpretation and knowledge ...
Margaret E. O'Hara, Kiera McDuff, Hannah Wei, Lisa McCorkell, Catherine Thomson, Mary Kelly, Susie Goulding, Imelda O'Donovan, Sarah O'Connell, Ruth Stokes, Nisa Malli, Natalie St. Clair‐Sullivan, Soo Chan Carusone, Angela M. Cheung, Kristine M. Erlandson, Ciaran Bannan, Liam Townsend, Colm Bergin, Jaime H. Vera, Richard Harding, Lisa Avery, Darren A. Brown, Kelly K. O'Brien   +22 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Patients with post-COVID-19 condition show minor blood transcriptomic changes, with altered erythrocyte gene expression in a male subgroup

Frontiers in Immunology
BackgroundThe mechanisms underlying persistent symptoms after non-severe COVID-19 remain unclear. This study aimed to investigate transcriptomic changes in peripheral blood cells of patients with post-COVID-19 condition (PCC) and assess if distinct ...
Piia Karisola, Mari Kanerva, Mari Kanerva, Aki Vuokko, Helena Liira, Shuyuan Wang, Kirsi Kvarnström, Mikko Varonen, Hille Suojalehto, Harri Alenius, Harri Alenius   +10 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Barriers to healthcare access and experiences of stigma: Findings from a coproduced Long Covid case‐finding study

Health Expectations
Background and Aim Long Covid is often stigmatised, particularly in people who are disadvantaged within society. This may prevent them from seeking help and could lead to widening health inequalities. This coproduced study with a Community Advisory Board
Donna Clutterbuck, Mel Ramasawmy, Marija Pantelic, Jasmine Hayer, Fauzia Begum, Mark Faghy, Nayab Nasir, Barry Causer, Melissa Heightman, Gail Allsopp, Dan Wootton, M. Asad Khan, Claire Hastie, Monique Jackson, Clare Rayner, Darren Brown, Emily Parrett, Geraint Jones, Rowan Clarke, Sammie Mcfarland, Mark Gabbay, Amitava Banerjee, Nisreen A. Alwan, The STIMULATE‐ICP Consortium   +23 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Long Covid, invisible illness

Résumé Exécutif Contexte et justification Les évolutions cliniques après une infection par le SARS-CoV-2 vont d’une maladie asymptomatique à un accident cérébral majeur ou une pneumonie potentiellement mortelle, avec des séquelles post-aiguës ...
Reseau de Recherche Long Covid,, Jamoulle, Marc   +1 more
core   +2 more sources