Results 61 to 70 of about 15,297,754 (301)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome [PDF]

open access: yes, 2008
Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of the human chromosome 21 (Hsa21). Recently, O’Doherty and colleagues in an earlier study generated a new genetic mouse model of DS (Tc1) that carries an almost complete ...
Morice, E.   +6 more
core  

Performance- and stimulus-dependent oscillations in monkey prefrontal cortex during short-term memory [PDF]

open access: yes, 2009
Short-term memory requires the coordination of sub-processes like encoding, retention, retrieval and comparison of stored material to subsequent input. Neuronal oscillations have an inherent time structure, can effectively coordinate synaptic integration
Rodriguez, E.F.   +31 more
core   +1 more source

An LSTM-Based Method with Attention Mechanism for Travel Time Prediction

open access: yesSensors, 2019
Traffic prediction is based on modeling the complex non-linear spatiotemporal traffic dynamics in road network. In recent years, Long Short-Term Memory has been applied to traffic prediction, achieving better performance.
Xiangdong Ran   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Serial order in short-term memory [PDF]

open access: yes, 2001
How do we maintain a novel sequence of items in the correct order? For example, how do we remember the car number plate at the scene of a crime? Or how do we remember an unfamiliar telephone number during the few seconds between putting down the ...
Henson, R.N.A.
core  

Relational and conjunctive binding functions dissociate in short-term memory [PDF]

open access: yes, 2015
Remembering complex events requires binding features within unified objects (conjunctions) and holding associations between objects (relations). Recent studies suggest that the two functions dissociate in long-term memory (LTM). Less is known about their
Della Sala, Sergio   +7 more
core   +1 more source

Long-term and short-term memory networks based on forgetting memristors

open access: yesSoft Computing, 2022
Abstract The hardware circuit of neural network based on forgetting memristor not only has the characteristics of high computational efficiency and low power consumption, but also has the advantage that a memristor can store the weight of long-term memory and short-term memory.
Yi Liu   +5 more
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Explaining short-term memory phenomena with long-term memory theory: Is a special state involved? [PDF]

open access: yes, 2023
The idea that some recently encountered items reside in a special state where they do not have to be retrieved has come to be a critical component of short-term memory theories.
Humphreys, Michael S.   +7 more
core   +1 more source

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