Results 81 to 90 of about 371,915 (351)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

The Lancet Healthy Longevity: Health For All, For Longer

The Lancet. Healthy Longevity, 2020
The Lancet Healthy Longevity
doaj   +1 more source

Building a model for predicting and assessing the risk of developing pressure sores in low-mobility geriatric patients

Российский журнал гериатрической медицины
Background. It has been established that senile xerosis or “fragility” of the skin occurs in 75 % of the population over 65 years of age, when pathological skin dryness leads to peeling, the formation of microcracks, the appearance of senile itching ...
A. S. Bashkiryova, N. P. Baranova, D. Yu. Bogdanova, A. V. Shishko, P. P. Anikeev   +4 more
doaj   +1 more source

Small nucleoli are a cellular hallmark of longevity

Nature Communications, 2017
Animal lifespan is regulated by conserved metabolic signalling pathways and specific transcription factors, but whether these pathways affect common downstream mechanisms remains largely elusive.
Varnesh Tiku, Varnesh Tiku, Chirag Jain, Y. Raz, Shuhei Nakamura, Bree N. Heestand, Wei Liu, Martin R. Späth, H. Suchiman, R. Müller, P. Slagboom, L. Partridge, L. Partridge, Adam Antebi, Adam Antebi   +14 more
semanticscholar   +1 more source

Boosting the Energy Density of “Anode‐Free” Lithium Metal Batteries via Electrospun Polymeric Scaffolds

Advanced Functional Materials, EarlyView.
While host structures are known to enhance the reversibility and safety of lithium metal deposition, their additional volume and weight often decrease the battery's energy density and specific energy. By combining a lightweight and porous scaffold of electrospun polymer with a thinner separator, this article demonstrates a simultaneous improvement of ...
Lennart Wichmann, Bärbel Tengen, Peng Yan, Peter Lennartz, Isidora Cekic‐Laskovic, Martin Winter, Gunther Brunklaus   +6 more
wiley   +1 more source

Innovative gerontotechnologies “Age-Friendly Workplaces” as a basis for the professional longevity management

Российский журнал гериатрической медицины
Background. In the context of demographic aging, depopulation and workforce deficiency in Russia, the need for employment of aged workers will grow every year.
A. S. Bashkireva, N. P. Baranova, D. Yu. Bogdanova, A. V. Shishko, P. P. Anikeev   +4 more
doaj   +1 more source

Nature‐Inspired Sustainable Cooling for Photovoltaics with Enhanced Temperature‐Salinity Dynamics

Advanced Functional Materials, EarlyView.
Addressing solar panel overheating, a nature‐inspired cooling system mimicking ocean currents is developed. A moisture‐absorbing solution layer uses sunlight, radiative cooling, and moisture processes to create temperature/salinity gradients, accelerating circulation. The prototype cools panels by up to 18.2 °C under sunlight, sustains cooling, rapidly
Fuxiang Li, Zengguang Sui, Haosheng Lin, Yunren Sui, Francesco Vanin, Chunlei Zhang, Zonglong Zhu, Wei Wu   +7 more
wiley   +1 more source

Ethanol Extract of Oldenlandia diffusa – an Effective Chemotherapeutic for the Treatment of Colorectal Cancer in Humans -Anti-Cancer Effects of Oldenlandia diffusa-

Journal of Pharmacopuncture, 2016
Objectives: Oldenlandia diffusa is traditionally used to relieve the symptoms of and to treat various diseases, but its anti-cancer activity has not been well studied.
Soojin Lee, Ji Hwan Shim, Huijin Gim, Hyun Soo Park, Byung Joo Kim   +4 more
doaj   +1 more source

The Impact of Model Uncertainty on Index-Based Longevity Hedging and Measurement of Longevity Basis Risk [PDF]

, 2020
Uditha Balasooriya, Johnny Siu‐Hang Li, Jackie Li   +2 more
openalex   +1 more source

Functional Materials for Environmental Energy Harvesting in Smart Agriculture via Triboelectric Nanogenerators

Advanced Functional Materials, EarlyView.
This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva, Giulio Fatti, Emanuel Carlos, Guilherme Ferreira, Sumita Goswami, Suman Nandy, Luiz H. C. Mattoso, Elvira Fortunato, Caio G. Otoni, Rodrigo Martins   +9 more
wiley   +1 more source