Results 111 to 120 of about 810,836 (243)

Longevity Risk and Natural Hedge Potential in Portfolios Of Life Insurance Products: The Effect of Investment Risk [PDF]

open access: yes
Payments of life insurance products depend on the uncertain future evolution of survival probabilities. This uncertainty is referred to as longevity risk.
De Waegenaere, A.M.B.   +2 more
core  

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

Competition and Car Longevity [PDF]

open access: yes
We examine determinants of the nearly 30 percent increase in the average age of domestically produced, registered automobiles since the mid-1960s. We find that very little of the increase in car longevity is attributable to improvements in the inherent ...
Macauley, Molly, Hamilton, Bruce
core  

Longevity

open access: yes, 2015
Longevity and dart ...
Kazuki Kimura (3247128)   +3 more
core   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Got to practice / melody and lyric by Carrie Jacobs-Bond.

open access: yes, 1917
For voice and piano.Cover title.Cover illustration: child seated, practicing at a piano.Archived web ...
Jacobs-Bond, Carrie, 1862-1946
core  

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

open access: yesAdvanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters   +12 more
wiley   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

open access: yesAdvanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh   +8 more
wiley   +1 more source

Comparative evaluation of shear bond strength of nano-hybrid composites to dentin: influence of universal adhesives versus two-step etch-and-rinse adhesives

open access: yesDiscover Applied Sciences
Introduction and objective The clinical longevity of composite restorations relies on strong, long-lasting adhesion to dental tissues, minimizing microleakage and its associated complications such as bacterial infiltration, secondary caries, and pulp ...
Soodabeh Shoale   +3 more
doaj   +1 more source

Longevity

open access: yes, 2019
The file contain data for longevity of two ...
Cong Chen (325493)   +7 more
core   +1 more source

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