Results 121 to 130 of about 1,377,161 (326)

Modeling Longevity Risk using Extreme Value Theory: An Empirical Investigation using Portuguese and Spanish Population Data [PDF]

, 2012
Extreme value theory (EVT) provides a framework to formalize the study of behaviour in the tails of a distribution. In this paper we use EVT to model the statistical behaviour of mortality rates over a given high threshold age and to estimate the ...
Bravo, Jorge, Real, Pedro
core  

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Soft Actuators Integrated with Control and Power Units: Approaching Wireless Autonomous Soft Robots

Advanced Robotics Research, EarlyView.
Soft robots exhibit significant development potential in various applications. However, there are still key technical challenges regarding material improvement, structure design and components integration. This review focuses on the development and challenge of soft actuators, power components, and control components in untethered intelligent soft ...
Renwu Shi, Feifei Pan, Xiaobin Ji
wiley   +1 more source

Valuation and hedging of the ruin-contingent life annuity (RCLA) [PDF]

, 2012
This paper analyzes a novel type of mortality contingent-claim called a ruin-contingent life annuity (RCLA). This product fuses together a path-dependent equity put option with a "personal longevity" call option. The annuitant's (i.e.
Huang, Huaxiong, Milevsky, Moshe A., Salisbury, Thomas S.   +2 more
core   +1 more source

From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures

Advanced Robotics Research, EarlyView.
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science
Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in ...
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
doaj   +1 more source

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, EarlyView.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source

Growth and longevity of the endangered freshwater pearl mussel (Margaritifera margaritifera): Implications for conservation and management

Aquatic conservation
Key life‐history data, such as growth and age, are necessary to effectively manage and conserve threatened freshwater mussel species. Traditionally growth and age studies require large yet destructive sample sizes covering all age classes.
Sabrina Nykänen, J. Taskinen, M. Hajisafarali, A. Kuparinen   +3 more
semanticscholar   +1 more source

Climate change and variability, energy and disaster management: produced risks without produced solutions: rethinking the approach [PDF]

, 2008
Accelerated climate change and increasing climate variability is the single largest threat to the international goals of sustainable development, the Millennium Development Goals (MDGs) and disaster risk reduction.
O'Brien, Geoff, O'Keefe, Phil, Rose, Joanne, Wilson, Leanne   +3 more
core   +1 more source

Climate Action Impacts on Steelmaking Emissions of Persistent Organic Pollutants Highlight a Gap Between the Paris Agreement and the Stockholm Convention

Advanced Science, EarlyView.
Emissions of unintentionally produced persistent organic pollutants (UPOPs) and global warming are two major environmental challenges. But their governance has largely evolved in parallel, leaving the toxicity implications of climate‐driven industrial transitions poorly understood.
Yuxiang Sun, Qiuting Yang, Jianghui Yun, Yujue Yang, Junhao Tang, Qian Liu, Minghui Zheng, Guorui Liu   +7 more
wiley   +1 more source