Results 51 to 60 of about 1,377,161 (326)

Hedging Brevity Risk with Mortality-based Securities [PDF]

open access: yes, 2006
In 2003, Swiss Re introduced a mortality-based security designed to hedge excessive mortality changes for its life book of business. The concern was apparently brevity risk, i.e., the risk of premature death.
MacMinn, Richard, Richter, Andreas
core   +2 more sources

Chapter 4: ‘Helping Savers to Manage Longevity Risk’ [PDF]

open access: yesSSRN Electronic Journal, 2016
A particularly important issue in retirement income provision is longevity risk. There are two components to longevity risk. The first is the uncertainty over how long any particular pension scheme member is going to live after retirement. This is known as idiosyncratic longevity risk. Both individuals and schemes face idiosyncratic longevity risk. The
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Breaking the Mortality Curve: Investment-Driven Acceleration in Life Expectancy and Insurance Innovation

open access: yesRisks
Capital investment in longevity science—research targeting the biological processes of aging through interventions like cellular reprogramming, AI-driven drug discovery, and biological age monitoring—may create significant divergence between traditional ...
David M. Dror
doaj   +1 more source

Post-transplant lymphoproliferative disease after pediatric kidney transplant

open access: yesFrontiers in Pediatrics, 2022
Post-transplant lymphoproliferative disease (PTLD) is the most common malignancy complicating solid organ transplantation (SOT) in adults and children.
Rosanna Fulchiero   +2 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Welcome to the age of longevity capitalism

open access: yesFinance and Society
This essay coins and develops the concept of Longevity Capitalism, a biopolitical and financial regime in which both the condition of living longer and the pursuit of longevity are transformed into frontiers of accumulation.
Giulia Dal Maso
doaj   +1 more source

Longevity and mortality of owned dogs in England [PDF]

open access: yes, 2013
Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity.
Brodbelt, D C   +5 more
core   +3 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Pre-Weaned Calf Rearing on Northern Irish Dairy Farms: Part 1. A Description of Calf Management and Housing Design

open access: yesAnimals, 2021
The first few months of life are of great importance to the longevity and lifetime performance of dairy cows. The nutrition, environment and healthcare management of heifer calves must be sufficient to minimise exposure to stress and disease and enable ...
Aaron J Brown   +5 more
doaj   +1 more source

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